Flexeril vs. Ambien


We compare the side effects and drug effectiveness of Flexeril and Ambien. The study is created by eHealthMe based on reports of 182,501 people who take Flexeril and Ambien, and is updated regularly.

What's eHealthMe?

eHealthMe is a health data analysis company based in Mountain View, California. eHealthMe monitors and analyzes the outcomes of drugs and supplements that are currently on the market. The results are readily available to health care professionals and consumers.

eHealthMe has released original studies on market drugs and worked with leading universities and institutions such as IBM, London Health Science Centre, Mayo Clinic, Northwestern University and VA. eHealthMe studies have now been referenced in over 500 peer-reviewed medical publications.

How we gather our data?

Healthcare data is obtained from a number of sources including the Food and Drug Administration (FDA). This information is aggregated and used to produce personalized reports that patients can reference.

The information that eHealthMe collects includes:

  • Side effects (including severity and how people recover from them)
  • Associated conditions or symptoms
  • Drug effectiveness
  • Demographic data regarding drug use

How the study uses the data?

The study is based on cyclobenzaprine hydrochloride and zolpidem tartrate (the active ingredients of Flexeril and Ambien, respectively), and Flexeril and Ambien (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered.

What is Flexeril?

Flexeril has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms. (latest outcomes from Flexeril 30,282 users)

What is Ambien?

Ambien has active ingredients of zolpidem tartrate. It is often used in insomnia. (latest outcomes from Ambien 75,817 users)

How to use the study?

Patients can bring a copy of the report to their healthcare provider to ensure that all drug risks and benefits are fully discussed and understood. It is recommended that patients use the information presented as a part of a broader decision-making process.

On Mar, 09, 2019

182,501 people who take Flexeril and Ambien are studied.

Number of reports submitted per year:

Flexeril vs Ambien drug comparison reports.

Drugs in this study:

  • Ambien (zolpidem tartrate)
  • Flexeril (cyclobenzaprine hydrochloride)

eHealthMe real world results:

Most common side effects:

  1. Nausea (feeling of having an urge to vomit)
  2. Fatigue (feeling of tiredness)
  3. Pain
  4. Drug Ineffective
  5. Anxiety
  6. Dyspnoea (difficult or laboured respiration)
  7. Headache (pain in head)
  8. Diarrhoea
  9. Depression
  10. Fall
  1. Pain
  2. Nausea (feeling of having an urge to vomit)
  3. Fatigue (feeling of tiredness)
  4. Headache (pain in head)
  5. Drug Ineffective
  6. Anxiety
  7. Dyspnoea (difficult or laboured respiration)
  8. Depression
  9. Arthralgia (joint pain)
  10. Diarrhoea

Most common side effects experienced by people in long term use:

  1. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  2. Anxiety
  3. Depression
  4. Somnambulism (sleep walking)
  5. Road Traffic Accident
  6. Fall
  7. Pain
  8. Drug Ineffective
  9. Sleep Walking (walking during sleep)
  10. Abnormal Behaviour
  1. Depression
  2. Anxiety
  3. Pain
  4. Dizziness
  5. Suicide Attempt
  6. Injury
  7. Nausea (feeling of having an urge to vomit)
  8. Headache (pain in head)
  9. Chronic Kidney Disease
  10. Intentional Overdose

Drug effectiveness:

  • not at all: 2.16 %
  • somewhat: 16.69 %
  • moderate: 32.41 %
  • high: 33.38 %
  • very high: 15.36 %
  • not at all: 4.18 %
  • somewhat: 31.6 %
  • moderate: 38.88 %
  • high: 19.62 %
  • very high: 5.71 %

Do you take Flexeril or Ambien?

You are not alone:

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WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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