Intelence vs. Genvoya: side effect and effectiveness comparison - a phase IV clinical study
Summary:
We compare the side effects and drug effectiveness of Intelence and Genvoya. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 14,007 people who take Intelence and Genvoya, and is updated regularly. You can use the study as a second opinion to make health care decisions.
With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.
14,007 people who take Intelence and Genvoya are studied.
What is Intelence?
Intelence has active ingredients of etravirine. It is often used in hiv infection. eHealthMe is studying from 3,203 Intelence users for its effectiveness, alternative drugs and more.
What is Genvoya?
Genvoya has active ingredients of cobicistat; elvitegravir; emtricitabine; tenofovir alafenamide fumarate. It is often used in hiv infection. eHealthMe is studying from 7,654 Genvoya users for its effectiveness, alternative drugs and more.
Number of reports submitted per year:
Drugs being compared in this study:
- Intelence (etravirine)
- Genvoya (cobicistat; elvitegravir; emtricitabine; tenofovir alafenamide fumarate)
Most common side effects of the drugs, overall:
Most common side effects of the drugs, in long term (1+ years) use:
Drug effectiveness:
Intelence:
- not at all: 3.33 %
- somewhat: 0 %
- moderate: 13.33 %
- high: 36.67 %
- very high: 46.67 %
Genvoya:
- not at all: 0 %
- somewhat: 3.45 %
- moderate: 3.45 %
- high: 51.72 %
- very high: 41.38 %
Want to compare Intelence with Genvoya?
Personalize this study to your gender and age (0-99+).How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
Alternative drugs to, pros and cons of:
Common Intelence side effects:
- Acute kidney failure: 106 reports
- Anaemia (lack of blood): 141 reports
- Chronic kidney disease: 128 reports
- Death: 108 reports
- Depression: 110 reports
- Diarrhea: 105 reports
- Diplopia (double vision): 132 reports
- Eyelid ptosis (falling of the upper or lower eyelid): 138 reports
- Fever: 108 reports
- Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 136 reports
- Lipodystrophy acquired (a regional loss of subcutaneous adipose tissue which usually starts in the face, extends downward acquired): 297 reports
- Mitochondrial toxicity (a condition in which the mitochondria of a body's cells become damaged or decline significantly in number;): 143 reports
- Nausea (feeling of having an urge to vomit): 110 reports
- Pain: 217 reports
- Progressive external ophthalmoplegia (eye disorder characterized by slowly progressive inability to move the eyes and eyebrows): 102 reports
- Rashes (redness): 192 reports
- Stress and anxiety: 193 reports
Common Genvoya side effects:
- Acute kidney failure: 1,389 reports
- Anhedonia (inability to experience pleasure from activities usually found enjoyable): 1,141 reports
- Aseptic necrosis (the death of bone tissue due to a lack of blood supply): 1,692 reports
- Blood creatinine increased: 316 reports
- Bone density decreased: 3,229 reports
- Bone loss: 1,693 reports
- Broken bone: 580 reports
- Depression: 279 reports
- Diarrhea: 109 reports
- Drug ineffective: 102 reports
- Emotional distress: 1,388 reports
- Fatigue (feeling of tiredness): 159 reports
- Foot fracture: 140 reports
- Joint pain: 115 reports
- Multiple fractures: 1,196 reports
- Nausea (feeling of having an urge to vomit): 121 reports
- Osteoarthritis (a joint disease caused by cartilage loss in a joint): 135 reports
- Osteopenia (a condition where bone mineral density is lower than normal): 759 reports
- Osteoporosis (bones weak and more likely to break): 1,369 reports
- Pain: 1,425 reports
- Rashes (redness): 110 reports
- Renal impairment (severely reduced kidney function): 290 reports
- Renal injury (kidney injury): 1,594 reports
- Stress and anxiety: 1,218 reports
- Tooth injury: 303 reports
- Tooth loss: 1,644 reports
- Weight increased: 158 reports
How the study uses the data?
The study is based on etravirine and cobicistat; elvitegravir; emtricitabine; tenofovir alafenamide fumarate (the active ingredients of Intelence and Genvoya, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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