Lasix vs. Spironolactone: side effect and effectiveness comparison - a phase IV clinical study
Summary:
We compare the side effects and drug effectiveness of Lasix and Spironolactone. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 547,421 people who take Lasix and Spironolactone, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
547,421 people who take Lasix and Spironolactone are studied.
What is Lasix?
Lasix has active ingredients of furosemide. It is often used in swelling. eHealthMe is studying from 198,457 Lasix users for its effectiveness, alternative drugs and more.
What is Spironolactone?
Spironolactone has active ingredients of spironolactone. It is often used in acne. eHealthMe is studying from 102,118 Spironolactone users for its effectiveness, alternative drugs and more.
Number of reports submitted per year:

Drugs being compared in this study:
- Spironolactone (spironolactone)
- Lasix (furosemide)
Most common side effects of the drugs, overall:
Most common side effects of the drugs, in long term (1+ years) use:
Drug effectiveness:
Lasix:
- not at all: 3.19 %
- somewhat: 20.54 %
- moderate: 36.51 %
- high: 31.31 %
- very high: 8.44 %
Spironolactone:
- not at all: 4.53 %
- somewhat: 21.19 %
- moderate: 31.24 %
- high: 28.0 %
- very high: 15.04 %
Want to compare Lasix with Spironolactone?
Personalize this study to your gender and age (0-99+).How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Ochoa PS, Fisher T, "A 7‐Year Case of Furosemide‐Induced Immune Thrombocytopenia", Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 2013 Jul .
Related studies
Alternative drugs to, pros and cons of:
- Lasix (196,377 reports)
- Spironolactone (98,744 reports)
Common Lasix side effects:
- Breathing difficulty: 16,882 reports
- Fatigue (feeling of tiredness): 12,880 reports
- Weakness: 12,198 reports
- Pneumonia: 11,196 reports
- Diarrhea: 11,079 reports
- Pain: 10,881 reports
Browse all side effects of Lasix:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Spironolactone side effects:
- Breathing difficulty: 8,125 reports
- Fatigue (feeling of tiredness): 6,809 reports
- Hypotension (abnormally low blood pressure): 5,698 reports
- Diarrhea: 5,611 reports
- Dizziness: 5,097 reports
Browse all side effects of Spironolactone:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study is based on furosemide and spironolactone (the active ingredients of Lasix and Spironolactone, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Ginkgo Biloba and Pain - a second ago
- Evotaz and Nausea And Vomiting - 6 seconds ago
- How effective is Effexor Xr for Decreased Activity? - 21 seconds ago
- How effective is Plaquenil for Polymyalgia Rheumatica? - 23 seconds ago
- Proscar and Toviaz drug interaction - 28 seconds ago
- High Blood Pressure and Decreased Activity - 33 seconds ago
- Atracurium Besylate and Doxazosin Mesylate drug interaction - 37 seconds ago
- Pain and Decreased Activity - 38 seconds ago
- Jakafi and Decreased Activity - 43 seconds ago
- L-Methylfolate vs. Diazepam - 53 seconds ago