Lidocaine vs. Robaxin: side effect and effectiveness comparison - a phase IV clinical study
Summary:
We compare the side effects and drug effectiveness of Lidocaine and Robaxin. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 48,942 people who take Lidocaine and Robaxin, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
On Dec, 03, 2022
48,942 people who take Lidocaine and Robaxin are studied.
What is Lidocaine?
Lidocaine has active ingredients of lidocaine. It is often used in pain. eHealthMe is studying from 15,232 Lidocaine users for its effectiveness, alternative drugs and more.
What is Robaxin?
Robaxin has active ingredients of methocarbamol. It is often used in muscle spasms. eHealthMe is studying from 8,362 Robaxin users for its effectiveness, alternative drugs and more.
Number of reports submitted per year:
Drugs being compared in this study:
- Robaxin (methocarbamol)
- Lidocaine (lidocaine)
Most common side effects of the drugs, overall:
Most common side effects of the drugs, in long term (1+ years) use:
Drug effectiveness:
Lidocaine:
- not at all: 3.64 %
- somewhat: 35.45 %
- moderate: 28.18 %
- high: 20.91 %
- very high: 11.82 %
Robaxin:
- not at all: 5.36 %
- somewhat: 36.87 %
- moderate: 36.0 %
- high: 17.51 %
- very high: 4.27 %
Want to compare Lidocaine with Robaxin?
Personalize this study to your gender and age (0-99+).How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
Alternative drugs to, pros and cons of:
Common Lidocaine side effects:
- Abdominal discomfort: 110 reports
- Abdominal distension: 131 reports
- Abdominal pain: 431 reports
- Abdominal pain upper: 191 reports
- Acute kidney failure: 919 reports
- Agitation (state of anxiety or nervous excitement): 229 reports
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 179 reports
- Anaemia (lack of blood): 484 reports
- Anaesthetic complication: 101 reports
- Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 376 reports
- Anhedonia (inability to experience pleasure from activities usually found enjoyable): 550 reports
- Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat): 238 reports
- Arrhythmias (irregular heartbeat): 378 reports
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 214 reports
- Arthropathy: 103 reports
- Aseptic necrosis (the death of bone tissue due to a lack of blood supply): 134 reports
- Asthma: 163 reports
- Atelectasis (partial or complete collapse of the lung): 154 reports
- Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 349 reports
- Back pain: 669 reports
- Balance disorder: 127 reports
- Blood glucose increased: 156 reports
- Bone disorder: 267 reports
- Bradycardia (abnormally slow heart action): 324 reports
- Breathing difficulty: 845 reports
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 371 reports
- Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi): 124 reports
- Burning sensation: 128 reports
- Cardiac arrest: 438 reports
- Cardiac disorder: 144 reports
- Cardiac failure: 127 reports
- Cardiac failure congestive: 189 reports
- Cardiomyopathy (weakening of the heart muscle): 107 reports
- Cardio-respiratory arrest (sudden dysfunction of heart and lungs): 150 reports
- Cataract (clouding of the lens inside the eye): 157 reports
- Cellulitis (infection under the skin): 268 reports
- Chest pain: 548 reports
- Chills (felling of cold): 251 reports
- Chronic kidney disease: 128 reports
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe): 212 reports
- Circulatory collapse: 101 reports
- Confusion: 117 reports
- Confusional state: 326 reports
- Consciousness - decreased: 133 reports
- Constipation: 402 reports
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 301 reports
- Coronary heart disease (narrowing or blockage of the coronary arteries): 135 reports
- Cough: 412 reports
- Death: 710 reports
- Decreased interest: 141 reports
- Deep venous thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 207 reports
- Deformity (disfigurement): 111 reports
- Dehydration (dryness resulting from the removal of water): 382 reports
- Dental caries: 111 reports
- Depression: 631 reports
- Diabetes: 148 reports
- Diarrhea: 618 reports
- Disability: 103 reports
- Dizziness: 733 reports
- Drowsiness: 284 reports
- Drug abuse and dependence: 123 reports
- Drug hypersensitivity: 177 reports
- Drug ineffective: 711 reports
- Drug toxicity: 153 reports
- Dry mouth: 102 reports
- Ear pain: 101 reports
- Emotional distress: 698 reports
- Enlarged heart: 126 reports
- Fainting (loss of consciousness and postural tone): 231 reports
- Fall: 660 reports
- Fatigue (feeling of tiredness): 1,048 reports
- Fear: 570 reports
- Febrile neutropenia (fever with reduced white blood cells): 153 reports
- Fever: 792 reports
- Gait disturbance: 335 reports
- Gallstones (stone formation by bile component): 107 reports
- Gastric ulcer (stomach ulcer): 106 reports
- Gastroesophageal reflux disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 291 reports
- General physical health deterioration (weak health status): 262 reports
- Grand mal convulsion (a type of generalized seizure that affects the entire brain): 122 reports
- Haematocrit decreased: 101 reports
- Haematuria (presence of blood in urine): 150 reports
- Haemoglobin decreased: 215 reports
- Haemorrhage (bleeding): 169 reports
- Haemorrhoids (a swollen vein or group of veins in the region of the anus): 118 reports
- Hair loss: 154 reports
- Hallucinations (sensations that appear real but are created by your mind): 141 reports
- Headache (pain in head): 948 reports
- Head injury: 257 reports
- Heart attack: 232 reports
- Heart palpitations (feelings or sensations that your heart is pounding or racing): 184 reports
- Heart rate decreased: 132 reports
- Heart rate increased: 207 reports
- Herpes zoster: 107 reports
- High blood cholesterol: 175 reports
- High blood pressure: 761 reports
- Hyperhidrosis (abnormally increased sweating): 186 reports
- Hyperkalemia (damage to or disease of the kidney): 105 reports
- Hypersensitivity: 184 reports
- Hypoaesthesia (reduced sense of touch or sensation): 368 reports
- Hypokalemia (low potassium): 160 reports
- Hypotension (abnormally low blood pressure): 984 reports
- Impaired healing: 210 reports
- Indigestion: 226 reports
- Infection: 355 reports
- Influenza like illness: 149 reports
- Injection site pain: 201 reports
- Injury: 894 reports
- Insomnia (sleeplessness): 346 reports
- Intervertebral disc degeneration (spinal disc degeneration): 178 reports
- Intervertebral disc protrusion (spinal disc protrusion): 142 reports
- Intestinal obstruction: 108 reports
- Itching: 345 reports
- Joint pain: 628 reports
- Joint swelling: 155 reports
- Kidney stones: 157 reports
- Loss of consciousness: 331 reports
- Low tissue oxygen: 177 reports
- Malaise (a feeling of general discomfort or uneasiness): 418 reports
- Memory loss: 299 reports
- Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 109 reports
- Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation): 140 reports
- Metastases to bone (cancer spreads to bone): 127 reports
- Migraine (headache): 178 reports
- Mitral valve incompetence (inefficient heart valve): 103 reports
- Multi-organ failure (multisystem organ failure): 424 reports
- Multiple myeloma (cancer of the plasma cells): 104 reports
- Muscle aches (muscle pain): 244 reports
- Muscle spasms (muscle contraction): 211 reports
- Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 177 reports
- Nausea (feeling of having an urge to vomit): 1,062 reports
- Nausea and vomiting: 676 reports
- Neck pain: 235 reports
- Neoplasm malignant (cancer tumour): 131 reports
- Nervousness: 148 reports
- Neuropathy peripheral (surface nerve damage): 227 reports
- Nosebleed (bleeding from nose): 116 reports
- Oedema (fluid collection in tissue): 200 reports
- Oedema peripheral (superficial swelling): 400 reports
- Oropharyngeal pain: 146 reports
- Osteoarthritis (a joint disease caused by cartilage loss in a joint): 241 reports
- Osteomyelitis (infection of bone): 235 reports
- Osteonecrosis of jaw (death of bone of jaw): 338 reports
- Osteoporosis (bones weak and more likely to break): 165 reports
- Otitis (ear infection): 131 reports
- Overdose: 271 reports
- Oxygen saturation decreased: 156 reports
- Pain: 1,948 reports
- Pain in extremity: 341 reports
- Pain in jaw: 194 reports
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 146 reports
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 291 reports
- Pleural effusion (water on the lungs): 211 reports
- Pneumonia: 773 reports
- Post procedural complication: 125 reports
- Pulmonary embolism (blockage of the main artery of the lung): 201 reports
- Pulmonary oedema (fluid accumulation in the lungs): 206 reports
- Rashes (redness): 630 reports
- Rectal haemorrhage (bleeding from anus): 144 reports
- Renal failure acute (rapid kidney dysfunction): 426 reports
- Renal failure chronic (long lasting kidney dysfunction): 119 reports
- Renal impairment (severely reduced kidney function): 445 reports
- Renal injury (kidney injury): 505 reports
- Respiratory acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 200 reports
- Respiratory distress (difficulty in breathing): 129 reports
- Rib fracture: 127 reports
- Sepsis (a severe blood infection that can lead to organ failure and death): 288 reports
- Sinusitis (inflammation of sinus): 694 reports
- Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node): 135 reports
- Skin blushing/flushing (a sudden reddening of the face, neck): 103 reports
- Sleep disorder: 122 reports
- Speech disorder: 102 reports
- Speech impairment (adult) (inability to speak (adult)): 165 reports
- Spinal osteoarthritis (joint cartilage loss in spine): 152 reports
- Stress and anxiety: 1,393 reports
- Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 255 reports
- Suicidal ideation: 109 reports
- Swallowing difficulty: 275 reports
- Swelling: 226 reports
- Swelling face: 116 reports
- The flu (the flu is caused by an influenza virus): 131 reports
- Thrombocytopenia (decrease of platelets in blood): 361 reports
- Tooth abscess (pus formation in tooth): 161 reports
- Tooth disorder (tooth disease): 123 reports
- Tooth extraction: 135 reports
- Tooth loss: 112 reports
- Tremor (trembling or shaking movements in one or more parts of your body): 202 reports
- Unresponsive to stimuli: 120 reports
- Urinary retention (the inability to completely or partially empty the bladder): 114 reports
- Urinary tract infection: 618 reports
- Urticaria (rash of round, red welts on the skin that itch intensely): 183 reports
- Ventricular extrasystoles (premature cardiac contraction): 104 reports
- Ventricular fibrillation (abnormally irregular heart rhythm): 150 reports
- Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart): 214 reports
- Vision blurred: 230 reports
- Visual acuity reduced (reduced clearness of vision): 119 reports
- Visual impairment: 107 reports
- Weakness: 720 reports
- Weight decreased: 483 reports
- Weight increased: 344 reports
- White blood cell count increased: 115 reports
Common Robaxin side effects:
- Abdominal discomfort: 142 reports
- Abdominal pain: 230 reports
- Abdominal pain upper: 212 reports
- Acute kidney failure: 155 reports
- Anaemia (lack of blood): 205 reports
- Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat): 167 reports
- Arrhythmias (irregular heartbeat): 101 reports
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 139 reports
- Asthma: 104 reports
- Back pain: 511 reports
- Balance disorder: 108 reports
- Bone disorder: 123 reports
- Breathing difficulty: 441 reports
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 172 reports
- Cardiac failure congestive: 152 reports
- Cellulitis (infection under the skin): 132 reports
- Chest pain: 343 reports
- Chills (felling of cold): 107 reports
- Chronic kidney disease: 155 reports
- Confusional state: 133 reports
- Constipation: 211 reports
- Cough: 208 reports
- Death: 129 reports
- Deep venous thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 119 reports
- Dehydration (dryness resulting from the removal of water): 127 reports
- Depression: 495 reports
- Diarrhea: 461 reports
- Dizziness: 472 reports
- Drowsiness: 243 reports
- Drug dependence: 127 reports
- Drug hypersensitivity: 295 reports
- Drug ineffective: 563 reports
- Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 112 reports
- Dry mouth: 107 reports
- Emotional distress: 182 reports
- Fainting (loss of consciousness and postural tone): 150 reports
- Fall: 474 reports
- Fatigue (feeling of tiredness): 600 reports
- Fever: 258 reports
- Fibromyalgia (a long-term condition which causes pain all over the body): 115 reports
- Gait disturbance: 207 reports
- Gastroesophageal reflux disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 164 reports
- Hair loss: 128 reports
- Headache (pain in head): 529 reports
- Head injury: 151 reports
- Heart attack: 174 reports
- Heart palpitations (feelings or sensations that your heart is pounding or racing): 168 reports
- Hiatal hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 103 reports
- High blood cholesterol: 151 reports
- High blood pressure: 401 reports
- Hyperhidrosis (abnormally increased sweating): 140 reports
- Hypersensitivity: 111 reports
- Hypoaesthesia (reduced sense of touch or sensation): 268 reports
- Hypotension (abnormally low blood pressure): 161 reports
- Indigestion: 136 reports
- Infection: 124 reports
- Injection site pain: 122 reports
- Injury: 180 reports
- Insomnia (sleeplessness): 358 reports
- Intervertebral disc protrusion (spinal disc protrusion): 176 reports
- Itching: 181 reports
- Joint pain: 412 reports
- Loss of consciousness: 135 reports
- Malaise (a feeling of general discomfort or uneasiness): 284 reports
- Memory loss: 253 reports
- Migraine (headache): 195 reports
- Muscle aches (muscle pain): 162 reports
- Muscle spasms (muscle contraction): 326 reports
- Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 109 reports
- Nausea (feeling of having an urge to vomit): 744 reports
- Nausea and vomiting: 381 reports
- Neck pain: 197 reports
- Neuropathy peripheral (surface nerve damage): 120 reports
- Oedema peripheral (superficial swelling): 208 reports
- Osteoarthritis (a joint disease caused by cartilage loss in a joint): 182 reports
- Osteonecrosis of jaw (death of bone of jaw): 121 reports
- Overdose: 119 reports
- Pain: 818 reports
- Pain in extremity: 415 reports
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 154 reports
- Pneumonia: 300 reports
- Pulmonary embolism (blockage of the main artery of the lung): 155 reports
- Rashes (redness): 303 reports
- Sinusitis (inflammation of sinus): 186 reports
- Sleep apnea syndrome: 136 reports
- Speech impairment (adult) (inability to speak (adult)): 101 reports
- Spinal osteoarthritis (joint cartilage loss in spine): 106 reports
- Stress and anxiety: 617 reports
- Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 137 reports
- Suicidal ideation: 131 reports
- Swallowing difficulty: 142 reports
- Swelling: 102 reports
- Tremor (trembling or shaking movements in one or more parts of your body): 215 reports
- Upper respiratory tract infection: 107 reports
- Urinary tract infection: 317 reports
- Vision blurred: 165 reports
- Weakness: 526 reports
- Weight decreased: 301 reports
- Weight increased: 265 reports
How the study uses the data?
The study is based on lidocaine and methocarbamol (the active ingredients of Lidocaine and Robaxin, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
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DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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