Lupron depot vs. Percocet: side effect and effectiveness comparison - a phase IV clinical study
Summary:
We compare the side effects and drug effectiveness of Lupron depot and Percocet. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 197,545 people who take Lupron depot and Percocet, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
197,545 people who take Lupron depot and Percocet are studied.
What is Lupron depot?
Lupron depot has active ingredients of leuprolide acetate. It is often used in endometriosis. eHealthMe is studying from 25,002 Lupron depot users for its effectiveness, alternative drugs and more.
What is Percocet?
Percocet has active ingredients of acetaminophen; oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 96,765 Percocet users for its effectiveness, alternative drugs and more.
Number of reports submitted per year:

Drugs being compared in this study:
- Percocet (acetaminophen; oxycodone hydrochloride)
- Lupron Depot (leuprolide acetate)
Most common side effects of the drugs, overall:
Most common side effects of the drugs, in long term (1+ years) use:
Drug effectiveness:
Lupron Depot:
- not at all: 9.82 %
- somewhat: 19.38 %
- moderate: 26.36 %
- high: 29.2 %
- very high: 15.25 %
Percocet:
- not at all: 1.77 %
- somewhat: 17.92 %
- moderate: 40.45 %
- high: 31.47 %
- very high: 8.39 %
Want to compare Lupron depot with Percocet?
Personalize this study to your gender and age (0-99+).How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Sharma SP, Muggia F, "Supraventricular tachycardia and urticaria complicating leuprolide-induced ovarian suppression in a young woman with breast cancer: a case report", ecancermedicalscience, 2016 Jan .
- Pong YH, Lu YC, Tsai VF, Huang PL, Hsieh JT, Chang HC, "Acute manic and psychotic symptoms following subcutaneous leuprolide acetate in a male patient without prior psychiatric history: A case report and literature review", Urological Science, 2014 Mar .
Related studies
Alternative drugs to, pros and cons of:
- Lupron depot (24,710 reports)
- Percocet (93,184 reports)
Common Lupron depot side effects:
- Hot flush (sudden feelings of heat): 3,453 reports
- Fatigue (feeling of tiredness): 1,790 reports
- Death: 1,636 reports
- Headache (pain in head): 1,485 reports
- Pain: 1,333 reports
- Weakness: 1,200 reports
Browse all side effects of Lupron depot:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Percocet side effects:
- Death: 15,739 reports
- Pain: 9,517 reports
- Fatigue (feeling of tiredness): 5,471 reports
- Stress and anxiety: 5,146 reports
Browse all side effects of Percocet:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study is based on leuprolide acetate and acetaminophen; oxycodone hydrochloride (the active ingredients of Lupron depot and Percocet, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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