Lyrica vs. Arthrotec


We compare the side effects and drug effectiveness of Lyrica and Arthrotec. The study is created by eHealthMe based on reports of 198,048 people who take Lyrica and Arthrotec, and is updated regularly.

What's eHealthMe?

eHealthMe is a health data analysis company based in Mountain View, California. eHealthMe monitors and analyzes the outcomes of drugs and supplements that are currently on the market. The results are readily available to health care professionals and consumers.

eHealthMe has released original studies on market drugs and worked with leading universities and institutions such as IBM, London Health Science Centre, Mayo Clinic, Northwestern University and VA. eHealthMe studies have now been referenced in over 500 peer-reviewed medical publications.

How we gather our data?

Healthcare data is obtained from a number of sources including the Food and Drug Administration (FDA). This information is aggregated and used to produce personalized reports that patients can reference.

The information that eHealthMe collects includes:

  • Side effects (including severity and how people recover from them)
  • Associated conditions or symptoms
  • Drug effectiveness
  • Demographic data regarding drug use

How the study uses the data?

The study is based on pregabalin and diclofenac sodium; misoprostol (the active ingredients of Lyrica and Arthrotec, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered.

What is Lyrica?

Lyrica has active ingredients of pregabalin. It is often used in fibromyalgia. (latest outcomes from Lyrica 172,120 users)

What is Arthrotec?

Arthrotec has active ingredients of diclofenac sodium; misoprostol. It is often used in arthritis. (latest outcomes from Arthrotec 8,373 users)

How to use the study?

Patients can bring a copy of the report to their healthcare provider to ensure that all drug risks and benefits are fully discussed and understood. It is recommended that patients use the information presented as a part of a broader decision-making process.

On Mar, 14, 2019

198,048 people who take Lyrica and Arthrotec are studied.

Number of reports submitted per year:

Lyrica vs Arthrotec drug comparison reports.

Drugs in this study:

  • Arthrotec (diclofenac sodium; misoprostol)
  • Lyrica (pregabalin)

Most common side effects:

  1. Drug Ineffective
  2. Nausea (feeling of having an urge to vomit)
  3. Diarrhoea
  4. Arthralgia (joint pain)
  5. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints)
  6. Fatigue (feeling of tiredness)
  7. Headache (pain in head)
  8. Dyspnoea (difficult or laboured respiration)
  9. Drug Hypersensitivity
  10. Fall
  1. Drug Ineffective
  2. Dizziness
  3. Weight Increased
  4. Nausea (feeling of having an urge to vomit)
  5. Malaise (a feeling of general discomfort or uneasiness)
  6. Somnolence (a state of near-sleep, a strong desire for sleep)
  7. Fatigue (feeling of tiredness)
  8. Pain In Extremity
  9. Fall
  10. Headache (pain in head)

Most common side effects experienced by people in long term use:

  1. Drug Ineffective
  2. Dyspnoea (difficult or laboured respiration)
  3. Cerebrovascular Accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  4. Haematemesis (vomiting of blood)
  5. Metastases To Lung (cancer spreads to lung)
  6. Arthralgia (joint pain)
  7. Renal Failure Acute (rapid kidney dysfunction)
  8. Diarrhoea
  9. Malaise (a feeling of general discomfort or uneasiness)
  10. Gastrointestinal Haemorrhage (bleeding gastrointestinal tract)
  1. Drug Ineffective
  2. Insomnia (sleeplessness)
  3. Pain In Extremity
  4. Weight Increased
  5. Nausea (feeling of having an urge to vomit)
  6. Malaise (a feeling of general discomfort or uneasiness)
  7. Depression
  8. Withdrawal Syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
  9. Dizziness
  10. Headache (pain in head)

Drug effectiveness:

  • not at all: 5.15 %
  • somewhat: 20.17 %
  • moderate: 42.06 %
  • high: 24.03 %
  • very high: 8.58 %
  • not at all: 6.92 %
  • somewhat: 28.17 %
  • moderate: 35.0 %
  • high: 22.77 %
  • very high: 7.13 %

Do you take Lyrica or Arthrotec?

You are not alone:

Related publications that referenced our studies

Related studies:

Recent updates

Recent general studies
Recent personal studies

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.