Meclizine vs. Zofran


We compare the side effects and drug effectiveness of Meclizine and Zofran. The study is created by eHealthMe based on reports of 76,039 people who take Meclizine and Zofran, and is updated regularly.

What's eHealthMe?

eHealthMe is a health data analysis company based in Mountain View, California. eHealthMe monitors and analyzes the outcomes of drugs and supplements that are currently on the market. The results are readily available to health care professionals and consumers.

eHealthMe has released original studies on market drugs and worked with leading universities and institutions such as IBM, London Health Science Centre, Mayo Clinic, Northwestern University and VA. eHealthMe studies have now been referenced in over 500 peer-reviewed medical publications.

How we gather our data?

Healthcare data is obtained from a number of sources including the Food and Drug Administration (FDA). This information is aggregated and used to produce personalized reports that patients can reference.

The information that eHealthMe collects includes:

  • Side effects (including severity and how people recover from them)
  • Associated conditions or symptoms
  • Drug effectiveness
  • Demographic data regarding drug use

How the study uses the data?

The study is based on meclizine hydrochloride and ondansetron hydrochloride (the active ingredients of Meclizine and Zofran, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered.

What is Meclizine?

Meclizine has active ingredients of meclizine hydrochloride. It is often used in dizziness. (latest outcomes from Meclizine 13,045 users)

What is Zofran?

Zofran has active ingredients of ondansetron hydrochloride. It is often used in nausea. (latest outcomes from Zofran 55,159 users)

How to use the study?

Patients can bring a copy of the report to their healthcare provider to ensure that all drug risks and benefits are fully discussed and understood. It is recommended that patients use the information presented as a part of a broader decision-making process.

On Mar, 20, 2019

76,039 people who take Meclizine and Zofran are studied.

Number of reports submitted per year:

Meclizine vs Zofran drug comparison reports.

Drugs in this study:

  • Zofran (ondansetron hydrochloride)
  • Meclizine (meclizine hydrochloride)

Most common side effects:

  1. Diarrhoea
  2. Pain
  3. Fatigue (feeling of tiredness)
  4. Dyspnoea (difficult or laboured respiration)
  5. Anxiety
  6. Pyrexia (fever)
  7. Dehydration (dryness resulting from the removal of water)
  8. Injury
  9. Headache (pain in head)
  10. Asthenia (weakness)
  1. Pain
  2. Fatigue (feeling of tiredness)
  3. Fall
  4. Dyspnoea (difficult or laboured respiration)
  5. Diarrhoea
  6. Headache (pain in head)
  7. Asthenia (weakness)
  8. Anxiety
  9. Drug Ineffective
  10. Back Pain

Most common side effects experienced by people in long term use:

  1. Anxiety
  2. Pain
  3. Emotional Distress
  4. Injury
  5. Maternal Exposure During Pregnancy (use of substance during pregnancy)
  6. Alopecia (absence of hair from areas of the body)
  7. Depression
  8. Arthralgia (joint pain)
  9. Drug Ineffective
  10. Headache (pain in head)
  1. Pain
  2. Anxiety
  3. Chronic Kidney Disease
  4. Dyspnoea (difficult or laboured respiration)
  5. Depression
  6. Iron Deficiency Anaemia
  7. Injury
  8. Therapeutic Response Unexpected
  9. Shock Haemorrhagic (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin due to excess bleeding)
  10. Deep Vein Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

Drug effectiveness:

  • not at all: 4.03 %
  • somewhat: 25.12 %
  • moderate: 35.07 %
  • high: 24.64 %
  • very high: 11.14 %
  • not at all: 3.61 %
  • somewhat: 33.73 %
  • moderate: 32.83 %
  • high: 22.29 %
  • very high: 7.53 %

Do you take Meclizine or Zofran?

You are not alone:

Related publications that referenced our studies

Related studies:

Compare Meclizine with similar drugs
Compare Zofran with similar drugs

Recent updates

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WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.