Mepergan vs. Topiramate: side effect and effectiveness comparison - a phase IV clinical study
We compare the side effects and drug effectiveness of Mepergan and Topiramate. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 96,448 people who take Mepergan and Topiramate, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
96,448 people who take Mepergan and Topiramate are studied.
What is Mepergan?
Mepergan has active ingredients of meperidine hydrochloride; promethazine hydrochloride. It is often used in pain. eHealthMe is studying from 202 Mepergan users for its effectiveness, alternative drugs and more.
What is Topiramate?
Topiramate has active ingredients of topiramate. It is often used in migraine. eHealthMe is studying from 40,597 Topiramate users for its effectiveness, alternative drugs and more.
Number of reports submitted per year:
Drugs being compared in this study:
- Mepergan (meperidine hydrochloride; promethazine hydrochloride)
- Topiramate (topiramate)
Most common side effects of the drugs, overall:
Most common side effects of the drugs, in long term (1+ years) use:
- not at all: 0 %
- somewhat: 33.33 %
- moderate: 66.67 %
- high: 0 %
- very high: 0 %
- not at all: 4.25 %
- somewhat: 20.24 %
- moderate: 29.69 %
- high: 28.59 %
- very high: 17.22 %
Want to compare Mepergan with Topiramate?Personalize this study to your gender and age (0-99+).
How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Baloch M, Siddiqui MA, "Topiramate induced sudden loss of vision", JPMA, 2012 Oct .
- Kocamaz, M., & Karadag, O., "Topiramate-Induced Acute Myopia, Diplopia, and Photosensitivity: A Case Report", Beyoglu Eye Journal, 2019 Jan .
Alternative drugs to, pros and cons of:
- Mepergan (190 reports)
- Topiramate (39,042 reports)
Common Topiramate side effects:
- Drug ineffective: 4,046 reports
- Headache (pain in head): 2,566 reports
- Fatigue (feeling of tiredness): 2,428 reports
- Dizziness: 1,720 reports
- Migraine (headache): 1,644 reports
- Pain: 1,627 reports
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 1,516 reports
- Drowsiness: 1,501 reports
Browse all side effects of Topiramate:a b c d e f g h i j k l m n o p q r s t u v w x y z
How the study uses the data?
The study is based on meperidine hydrochloride; promethazine hydrochloride and topiramate (the active ingredients of Mepergan and Topiramate, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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