Meperidine hydrochloride vs. Promethazine hydrochloride: side effect and effectiveness comparison - a phase IV clinical study
Summary:
We compare the side effects and drug effectiveness of Meperidine hydrochloride and Promethazine hydrochloride. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 65,365 people who take Meperidine hydrochloride and Promethazine hydrochloride, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
65,365 people who take Meperidine hydrochloride and Promethazine hydrochloride are studied.
What is Meperidine hydrochloride?
Meperidine hydrochloride has active ingredients of meperidine hydrochloride. It is often used in pain. eHealthMe is studying from 1,188 Meperidine hydrochloride users for its effectiveness, alternative drugs and more.
What is Promethazine hydrochloride?
Promethazine hydrochloride has active ingredients of promethazine hydrochloride. It is often used in nausea. eHealthMe is studying from 1,265 Promethazine hydrochloride users for its effectiveness, alternative drugs and more.
Number of reports submitted per year:

Drugs being compared in this study:
- Meperidine Hydrochloride (meperidine hydrochloride)
- Promethazine Hydrochloride (promethazine hydrochloride)
Most common side effects of the drugs, overall:
Most common side effects of the drugs, in long term (1+ years) use:
Drug effectiveness:
Meperidine Hydrochloride:
- not at all: 3.55 %
- somewhat: 18.44 %
- moderate: 40.43 %
- high: 29.79 %
- very high: 7.8 %
Promethazine Hydrochloride:
- not at all: 7.25 %
- somewhat: 19.96 %
- moderate: 31.83 %
- high: 28.68 %
- very high: 12.29 %
Want to compare Meperidine hydrochloride with Promethazine hydrochloride?
Personalize this study to your gender and age (0-99+).How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Teimoory M, Arefi M, Behnoush B, Bastani B, "Promethazine and Treatment Refractory Agitation in Clonidine Toxicity", International Journal of Medical Toxicology and Forensic Medicine, 2013 Mar .
Related studies
Alternative drugs to, pros and cons of:
- Meperidine hydrochloride (1,146 reports)
- Promethazine hydrochloride (886 reports)
Common Meperidine hydrochloride side effects:
- Pain: 208 reports
- Nausea and vomiting: 176 reports
- Drug ineffective: 131 reports
- Fever: 111 reports
- Fatigue (feeling of tiredness): 107 reports
Browse all side effects of Meperidine hydrochloride:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study is based on meperidine hydrochloride and promethazine hydrochloride (the active ingredients of Meperidine hydrochloride and Promethazine hydrochloride, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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