Methadone hydrochloride vs. Dilaudid: side effect and effectiveness comparison - a phase IV clinical study
Summary:
We compare the side effects and drug effectiveness of Methadone hydrochloride and Dilaudid. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 184,242 people who take Methadone hydrochloride and Dilaudid, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
184,242 people who take Methadone hydrochloride and Dilaudid are studied.
What is Methadone hydrochloride?
Methadone hydrochloride has active ingredients of methadone hydrochloride. It is often used in pain. eHealthMe is studying from 6,942 Methadone hydrochloride users for its effectiveness, alternative drugs and more.
What is Dilaudid?
Dilaudid has active ingredients of hydromorphone hydrochloride. It is often used in pain. eHealthMe is studying from 87,686 Dilaudid users for its effectiveness, alternative drugs and more.
Number of reports submitted per year:

Drugs being compared in this study:
- Dilaudid (hydromorphone hydrochloride)
- Methadone Hydrochloride (methadone hydrochloride)
Most common side effects of the drugs, overall:
Most common side effects of the drugs, in long term (1+ years) use:
Drug effectiveness:
Methadone Hydrochloride:
- not at all: 1.8 %
- somewhat: 14.88 %
- moderate: 31.57 %
- high: 31.85 %
- very high: 19.9 %
Dilaudid:
- not at all: 3.12 %
- somewhat: 20.77 %
- moderate: 36.9 %
- high: 32.26 %
- very high: 6.96 %
Want to compare Methadone hydrochloride with Dilaudid?
Personalize this study to your gender and age (0-99+).How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- McFarlane SI, "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2015 Jan .
- Ashkar AG, Goldberg T, Maraj I, Masters A, McFarlane SI, "Torsades De Pointes Induced by Methadone and Clonazepam Use", International Journal of Medical and Pharmaceutical Case Reports, 2015 Jan .
- McFarlane, S. I. , "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2014 Jan .
Related studies
Alternative drugs to, pros and cons of:
- Methadone hydrochloride (5,092 reports)
- Dilaudid (86,769 reports)
Common Methadone hydrochloride side effects:
- Drug abuse and dependence: 348 reports
- Pain: 329 reports
- Death: 293 reports
- Fatigue (feeling of tiredness): 254 reports
Browse all side effects of Methadone hydrochloride:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Dilaudid side effects:
- Pain: 19,487 reports
- Death: 15,851 reports
- Stress and anxiety: 4,137 reports
- Fatigue (feeling of tiredness): 3,611 reports
Browse all side effects of Dilaudid:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study is based on methadone hydrochloride and hydromorphone hydrochloride (the active ingredients of Methadone hydrochloride and Dilaudid, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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