Modafinil vs. Elavil: side effect and effectiveness comparison - a phase IV clinical study
Summary:
We compare the side effects and drug effectiveness of Modafinil and Elavil. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 154,811 people who take Modafinil and Elavil, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
154,811 people who take Modafinil and Elavil are studied.
What is Modafinil?
Modafinil has active ingredients of modafinil. It is often used in narcolepsy. eHealthMe is studying from 17,577 Modafinil users for its effectiveness, alternative drugs and more.
What is Elavil?
Elavil has active ingredients of amitriptyline hydrochloride. It is often used in depression. eHealthMe is studying from 19,557 Elavil users for its effectiveness, alternative drugs and more.
Number of reports submitted per year:
Drugs being compared in this study:
- Elavil (amitriptyline hydrochloride)
- Modafinil (modafinil)
Most common side effects of the drugs, overall:
Most common side effects of the drugs, in long term (1+ years) use:
Drug effectiveness:
Modafinil:
- not at all: 2.6 %
- somewhat: 17.71 %
- moderate: 33.56 %
- high: 32.49 %
- very high: 13.65 %
Elavil:
- not at all: 5.7 %
- somewhat: 26.5 %
- moderate: 34.67 %
- high: 24.56 %
- very high: 8.56 %
Want to compare Modafinil with Elavil?
Personalize this study to your gender and age (0-99+).How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Li W, Lamichhane J, "From Heartbreak to Left Bundle Branch Block: A Case of Amitriptyline Overdose", American Journal of Therapeutics, 2017 Sep .
- Lopes E, Pereira D, da Silva Behrens NS, de Almeida Fonseca H, Calvancanti PO, de Araújo Lima TF, Pradella-Hallinan M, Castro J, Tufik S, Coelho FM, "Cataplexy as a side effect of modafinil in a patient without narcolepsy", Sleep Science, 2014 Mar .
Related studies
Alternative drugs to, pros and cons of:
Common Modafinil side effects:
- Fatigue (feeling of tiredness): 1,589 reports
- Stress and anxiety: 1,140 reports
- Headache (pain in head): 1,106 reports
- High blood pressure: 1,101 reports
- Depression: 1,049 reports
- Drug ineffective: 1,000 reports
- Dizziness: 897 reports
Browse all side effects of Modafinil:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Elavil side effects:
- Pain: 2,351 reports
- Fatigue (feeling of tiredness): 2,006 reports
- Drug ineffective: 1,853 reports
- Stress and anxiety: 1,717 reports
- Weakness: 1,706 reports
- Joint pain: 1,613 reports
- Headache (pain in head): 1,594 reports
Browse all side effects of Elavil:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study is based on modafinil and amitriptyline hydrochloride (the active ingredients of Modafinil and Elavil, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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