Nabumetone vs. Cataflam: side effect and effectiveness comparison - a phase IV clinical study
Summary:
We compare the side effects and drug effectiveness of Nabumetone and Cataflam. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 25,584 people who take Nabumetone and Cataflam, and is updated regularly. You can use the study as a second opinion to make health care decisions.
With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.
25,584 people who take Nabumetone and Cataflam are studied.
What is Nabumetone?
Nabumetone has active ingredients of nabumetone. It is often used in arthritis. eHealthMe is studying from 8,594 Nabumetone users for its effectiveness, alternative drugs and more.
What is Cataflam?
Cataflam has active ingredients of diclofenac potassium. It is often used in pain. eHealthMe is studying from 1,700 Cataflam users for its effectiveness, alternative drugs and more.
Number of reports submitted per year:

Drugs being compared in this study:
- Cataflam (diclofenac potassium)
- Nabumetone (nabumetone)
Most common side effects of the drugs, overall:
Most common side effects of the drugs, in long term (1+ years) use:
Drug effectiveness:
Nabumetone:
- not at all: 5.11 %
- somewhat: 33.24 %
- moderate: 32.67 %
- high: 22.44 %
- very high: 6.53 %
Cataflam:
- not at all: 5.06 %
- somewhat: 27.22 %
- moderate: 29.11 %
- high: 30.38 %
- very high: 8.23 %
Want to compare Nabumetone with Cataflam?
Personalize this study to your gender and age (0-99+).How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Hung SC, Liao KF, Hung HC, Lin CL, Lai SW, Lin CH, "Nabumetone use and risk of acute pancreatitis in a case-control study", Pancreatology, 2016 Jun .
Related studies
Alternative drugs to, pros and cons of:
- Nabumetone (8,184 reports)
- Cataflam (1,606 reports)
Common Nabumetone side effects:
- Abdominal pain: 129 reports
- Abdominal pain upper: 144 reports
- Acute kidney failure: 190 reports
- Anaemia (lack of blood): 204 reports
- Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat): 133 reports
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 119 reports
- Back pain: 306 reports
- Bone disorder: 121 reports
- Breathing difficulty: 328 reports
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 117 reports
- Chest pain: 282 reports
- Chronic kidney disease: 246 reports
- Constipation: 136 reports
- Cough: 212 reports
- Death: 115 reports
- Deep venous thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 102 reports
- Depression: 271 reports
- Diarrhea: 347 reports
- Dizziness: 294 reports
- Drowsiness: 133 reports
- Drug hypersensitivity: 213 reports
- Drug ineffective: 558 reports
- Emotional distress: 144 reports
- Fall: 319 reports
- Fatigue (feeling of tiredness): 460 reports
- Fever: 221 reports
- Gait disturbance: 177 reports
- Gastroesophageal reflux disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 155 reports
- Hair loss: 129 reports
- Headache (pain in head): 397 reports
- Head injury: 121 reports
- High blood cholesterol: 130 reports
- High blood pressure: 280 reports
- Hypersensitivity: 108 reports
- Hypoaesthesia (reduced sense of touch or sensation): 166 reports
- Hypotension (abnormally low blood pressure): 141 reports
- Infection: 143 reports
- Injection site haemorrhage (bleeding from injection site): 116 reports
- Injection site pain: 171 reports
- Injection site reaction: 167 reports
- Injury: 176 reports
- Insomnia (sleeplessness): 197 reports
- Itching: 220 reports
- Joint pain: 415 reports
- Malaise (a feeling of general discomfort or uneasiness): 254 reports
- Memory loss: 158 reports
- Migraine (headache): 102 reports
- Muscle aches (muscle pain): 132 reports
- Muscle spasms (muscle contraction): 125 reports
- Nasopharyngitis (inflammation of the nasopharynx): 116 reports
- Nausea (feeling of having an urge to vomit): 509 reports
- Nausea and vomiting: 256 reports
- Neck pain: 122 reports
- Neuropathy peripheral (surface nerve damage): 115 reports
- Oedema peripheral (superficial swelling): 172 reports
- Osteoarthritis (a joint disease caused by cartilage loss in a joint): 157 reports
- Pain: 610 reports
- Pain in extremity: 312 reports
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 172 reports
- Peripheral swelling: 102 reports
- Pleural effusion (water on the lungs): 101 reports
- Pneumonia: 255 reports
- Psoriasis (immune-mediated disease that affects the skin): 110 reports
- Rashes (redness): 329 reports
- Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints): 141 reports
- Sinusitis (inflammation of sinus): 181 reports
- Spinal osteoarthritis (joint cartilage loss in spine): 101 reports
- Stress and anxiety: 394 reports
- Swallowing difficulty: 101 reports
- Thrombocytopenia (decrease of platelets in blood): 107 reports
- Tremor (trembling or shaking movements in one or more parts of your body): 113 reports
- Urinary tract infection: 157 reports
- Urticaria (rash of round, red welts on the skin that itch intensely): 112 reports
- Weakness: 342 reports
- Weight decreased: 192 reports
- Weight increased: 153 reports
Common Cataflam side effects:
- Drug ineffective: 121 reports
- Nausea (feeling of having an urge to vomit): 106 reports
- Pain: 155 reports
- Weakness: 121 reports
How the study uses the data?
The study is based on nabumetone and diclofenac potassium (the active ingredients of Nabumetone and Cataflam, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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