Orsythia vs. Norplant: side effect and effectiveness comparison - a phase IV clinical study
Summary:
We compare the side effects and drug effectiveness of Orsythia and Norplant. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 226,253 people who take Orsythia and Norplant, and is updated regularly. You can use the study as a second opinion to make health care decisions.
With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.
226,253 people who take Orsythia and Norplant are studied.
What is Orsythia?
Orsythia has active ingredients of ethinyl estradiol; levonorgestrel. It is often used in birth control. eHealthMe is studying from 329 Orsythia users for its effectiveness, alternative drugs and more.
What is Norplant?
Norplant has active ingredients of levonorgestrel. It is often used in birth control. eHealthMe is studying from 6,428 Norplant users for its effectiveness, alternative drugs and more.
Number of reports submitted per year:
Drugs being compared in this study:
- Norplant (levonorgestrel)
- Orsythia (ethinyl estradiol; levonorgestrel)
Most common side effects of the drugs, overall:
Most common side effects of the drugs, in long term (1+ years) use:
Drug effectiveness:
Orsythia:
- not at all: 0.99 %
- somewhat: 5.17 %
- moderate: 13.18 %
- high: 32.27 %
- very high: 48.4 %
Norplant:
- not at all: 3.08 %
- somewhat: 6.07 %
- moderate: 10.0 %
- high: 30.19 %
- very high: 50.65 %
Want to compare Orsythia with Norplant?
Personalize this study to your gender and age (0-99+).How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
Alternative drugs to, pros and cons of:
Common Orsythia side effects:
- Drug ineffective: 118 reports
- Emotional distress: 113 reports
- Pain: 120 reports
- Partner stress: 113 reports
- Pregnancy on oral contraceptive: 113 reports
- Stress and anxiety: 123 reports
Common Norplant side effects:
- Abortion spontaneous (naturally occurring miscarriage): 146 reports
- Accommodation disorder: 113 reports
- Application site pain: 101 reports
- Breast pain: 175 reports
- Chest pain: 177 reports
- Complication of drug device removal: 236 reports
- Depression: 810 reports
- Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 102 reports
- Drug ineffective: 153 reports
- Excessive or unwanted hair in women: 221 reports
- Fatigue (feeling of tiredness): 175 reports
- Hair loss: 871 reports
- Heavy or prolong menstrual bleeding: 805 reports
- Hypoaesthesia (reduced sense of touch or sensation): 495 reports
- Implant site reaction: 121 reports
- Injury: 304 reports
- Joint pain: 116 reports
- Libido decreased (loss of interest in sex): 107 reports
- Menometrorrhagia (a condition in which prolonged or excessive uterine bleeding occurs irregularly and more frequently than normal): 1,758 reports
- Menstruation irregular: 494 reports
- Migraine (headache): 305 reports
- Mood swings (an extreme or rapid change in mood): 448 reports
- Muscle aches (muscle pain): 108 reports
- Nausea (feeling of having an urge to vomit): 491 reports
- Nausea and vomiting: 158 reports
- Ovarian cysts (fluid filled sacs of the ovary): 304 reports
- Pain in limb: 406 reports
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 254 reports
- Pelvic pain: 189 reports
- Scar: 150 reports
- Skin disorder (skin disease): 146 reports
- Stress and anxiety: 160 reports
- Unintended pregnancy (unwanted pregnancies as well as those that are mistimed): 387 reports
- Vaginal bleeding between periods: 122 reports
- Vision blurred: 129 reports
- Weakness: 360 reports
- Weight decreased: 273 reports
- Weight increased: 1,616 reports
How the study uses the data?
The study is based on ethinyl estradiol; levonorgestrel and levonorgestrel (the active ingredients of Orsythia and Norplant, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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