Oxycodone hydrochloride vs. Advil pm: side effect and effectiveness comparison - a phase IV clinical study
Summary:
We compare the side effects and drug effectiveness of Oxycodone hydrochloride and Advil pm. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 323,946 people who take Oxycodone hydrochloride and Advil pm, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
323,946 people who take Oxycodone hydrochloride and Advil pm are studied.
What is Oxycodone hydrochloride?
Oxycodone hydrochloride has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 24,936 Oxycodone hydrochloride users for its effectiveness, alternative drugs and more.
What is Advil pm?
Advil pm has active ingredients of diphenhydramine hydrochloride; ibuprofen. It is often used in insomnia. eHealthMe is studying from 1,427 Advil pm users for its effectiveness, alternative drugs and more.
Number of reports submitted per year:

Drugs being compared in this study:
- Advil Pm (diphenhydramine hydrochloride; ibuprofen)
- Oxycodone Hydrochloride (oxycodone hydrochloride)
Most common side effects of the drugs, overall:
Most common side effects of the drugs, in long term (1+ years) use:
Drug effectiveness:
Oxycodone Hydrochloride:
- not at all: 1.67 %
- somewhat: 16.31 %
- moderate: 38.97 %
- high: 30.63 %
- very high: 12.42 %
Advil Pm:
- not at all: 4.23 %
- somewhat: 19.72 %
- moderate: 53.52 %
- high: 15.49 %
- very high: 7.04 %
Want to compare Oxycodone hydrochloride with Advil pm?
Personalize this study to your gender and age (0-99+).How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
Alternative drugs to, pros and cons of:
- Oxycodone hydrochloride (24,537 reports)
- Advil pm (1,137 reports)
Common Oxycodone hydrochloride side effects:
- Stress and anxiety: 1,321 reports
- Drug ineffective: 786 reports
- Drug abuse: 776 reports
- Depression: 712 reports
- Drug abuse and dependence: 701 reports
- Rashes (redness): 652 reports
- Itching: 592 reports
Browse all side effects of Oxycodone hydrochloride:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Advil pm side effects:
- Drug ineffective: 355 reports
- Drowsiness: 129 reports
Browse all side effects of Advil pm:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study is based on oxycodone hydrochloride and diphenhydramine hydrochloride; ibuprofen (the active ingredients of Oxycodone hydrochloride and Advil pm, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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