Paracetamol vs. Dolophine hydrochloride: side effect and effectiveness comparison - a phase IV clinical study
Summary:
We compare the side effects and drug effectiveness of Paracetamol and Dolophine hydrochloride. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 466,353 people who take Paracetamol and Dolophine hydrochloride, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
466,353 people who take Paracetamol and Dolophine hydrochloride are studied.
What is Paracetamol?
Paracetamol has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 114,992 Paracetamol users for its effectiveness, alternative drugs and more.
What is Dolophine hydrochloride?
Dolophine hydrochloride has active ingredients of methadone hydrochloride. It is often used in pain. eHealthMe is studying from 38 Dolophine hydrochloride users for its effectiveness, alternative drugs and more.
Number of reports submitted per year:

Drugs being compared in this study:
- Paracetamol (acetaminophen)
- Dolophine Hydrochloride (methadone hydrochloride)
Most common side effects of the drugs, overall:
Most common side effects of the drugs, in long term (1+ years) use:
Drug effectiveness:
Paracetamol:
- not at all: 6.19 %
- somewhat: 29.03 %
- moderate: 39.12 %
- high: 20.74 %
- very high: 4.92 %
Dolophine Hydrochloride:
- not at all: 2.19 %
- somewhat: 14.14 %
- moderate: 31.83 %
- high: 32.99 %
- very high: 18.85 %
Want to compare Paracetamol with Dolophine hydrochloride?
Personalize this study to your gender and age (0-99+).How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- McFarlane SI, "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2015 Jan .
- Ashkar AG, Goldberg T, Maraj I, Masters A, McFarlane SI, "Torsades De Pointes Induced by Methadone and Clonazepam Use", International Journal of Medical and Pharmaceutical Case Reports, 2015 Jan .
- McFarlane, S. I. , "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2014 Jan .
Related studies
Alternative drugs to, pros and cons of:
- Paracetamol (114,171 reports)
- Dolophine hydrochloride (18 reports)
Common Paracetamol side effects:
- Nausea and vomiting: 6,140 reports
- Fatigue (feeling of tiredness): 5,982 reports
- Fever: 5,542 reports
- Rashes (redness): 5,149 reports
- Diarrhea: 5,073 reports
- Headache (pain in head): 4,912 reports
- Breathing difficulty: 4,821 reports
Browse all side effects of Paracetamol:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study is based on acetaminophen and methadone hydrochloride (the active ingredients of Paracetamol and Dolophine hydrochloride, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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