Paroxetine hydrochloride vs. Desipramine hydrochloride: side effect and effectiveness comparison - a phase IV clinical study
Summary:
We compare the side effects and drug effectiveness of Paroxetine hydrochloride and Desipramine hydrochloride. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 148,015 people who take Paroxetine hydrochloride and Desipramine hydrochloride, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
148,015 people who take Paroxetine hydrochloride and Desipramine hydrochloride are studied.
What is Paroxetine hydrochloride?
Paroxetine hydrochloride has active ingredients of paroxetine hydrochloride. It is often used in depression. eHealthMe is studying from 8,496 Paroxetine hydrochloride users for its effectiveness, alternative drugs and more.
What is Desipramine hydrochloride?
Desipramine hydrochloride has active ingredients of desipramine hydrochloride. It is often used in depression. eHealthMe is studying from 246 Desipramine hydrochloride users for its effectiveness, alternative drugs and more.
Number of reports submitted per year:

Drugs being compared in this study:
- Paroxetine Hydrochloride (paroxetine hydrochloride)
- Desipramine Hydrochloride (desipramine hydrochloride)
Most common side effects of the drugs, overall:
Most common side effects of the drugs, in long term (1+ years) use:
Drug effectiveness:
Paroxetine Hydrochloride:
- not at all: 4.61 %
- somewhat: 19.03 %
- moderate: 34.02 %
- high: 30.74 %
- very high: 11.6 %
Desipramine Hydrochloride:
- not at all: 0 %
- somewhat: 30 %
- moderate: 45 %
- high: 15 %
- very high: 10 %
Want to compare Paroxetine hydrochloride with Desipramine hydrochloride?
Personalize this study to your gender and age (0-99+).How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Coskun M, Adak I, Akaltun I, "Bilateral gynecomastia in a preadolescent boy while under treatment with methylphenidate and paroxetine", Journal of clinical psychopharmacology, 2014 Aug .
Related studies
Alternative drugs to, pros and cons of:
- Paroxetine hydrochloride (7,554 reports)
- Desipramine hydrochloride (166 reports)
Common Paroxetine hydrochloride side effects:
- Stress and anxiety: 850 reports
- Suicidal ideation: 732 reports
- Dizziness: 719 reports
- Fatigue (feeling of tiredness): 716 reports
- Headache (pain in head): 644 reports
- Depression: 590 reports
- Drug ineffective: 522 reports
Browse all side effects of Paroxetine hydrochloride:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study is based on paroxetine hydrochloride and desipramine hydrochloride (the active ingredients of Paroxetine hydrochloride and Desipramine hydrochloride, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Cetirizine Hydrochloride and Polyneuropathy - 2 seconds ago
- Duspatalin and Asa drug interaction - 5 seconds ago
- Voriconazole and Seizures - 26 seconds ago
- Simponi Aria and Speech Disorder - 29 seconds ago
- Lovenox and Speech Impairment (Adult) - 31 seconds ago
- Tequin and Grand Mal Convulsion - 38 seconds ago
- Versed and Potassium drug interaction - 39 seconds ago
- Pyrazinamide and Peritoneal Effusion - 49 seconds ago
- Pepcid Rpd and Zofran drug interaction - 53 seconds ago
- How effective is Valium for Surgery? - a minute ago