Ponstel vs. Hydroxyzine pamoate: side effect and effectiveness comparison - a phase IV clinical study
Summary:
We compare the side effects and drug effectiveness of Ponstel and Hydroxyzine pamoate. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 10,299 people who take Ponstel and Hydroxyzine pamoate, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
10,299 people who take Ponstel and Hydroxyzine pamoate are studied.
What is Ponstel?
Ponstel has active ingredients of mefenamic acid. It is often used in pain. eHealthMe is studying from 448 Ponstel users for its effectiveness, alternative drugs and more.
What is Hydroxyzine pamoate?
Hydroxyzine pamoate has active ingredients of hydroxyzine pamoate. It is often used in stress and anxiety. eHealthMe is studying from 3,427 Hydroxyzine pamoate users for its effectiveness, alternative drugs and more.
Number of reports submitted per year:

Drugs being compared in this study:
- Ponstel (mefenamic acid)
- Hydroxyzine Pamoate (hydroxyzine pamoate)
Most common side effects of the drugs, overall:
Most common side effects of the drugs, in long term (1+ years) use:
Drug effectiveness:
Ponstel:
- not at all: 5.8 %
- somewhat: 15.94 %
- moderate: 31.88 %
- high: 39.13 %
- very high: 7.25 %
Hydroxyzine Pamoate:
- not at all: 4.6 %
- somewhat: 36.02 %
- moderate: 39.08 %
- high: 13.41 %
- very high: 6.9 %
Want to compare Ponstel with Hydroxyzine pamoate?
Personalize this study to your gender and age (0-99+).How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
Alternative drugs to, pros and cons of:
- Ponstel (394 reports)
- Hydroxyzine pamoate (3,079 reports)
Common Hydroxyzine pamoate side effects:
- Pain: 207 reports
- Stress and anxiety: 204 reports
- Drug ineffective: 195 reports
- Diarrhea: 144 reports
- Fatigue (feeling of tiredness): 139 reports
- Chronic kidney disease: 136 reports
Browse all side effects of Hydroxyzine pamoate:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study is based on mefenamic acid and hydroxyzine pamoate (the active ingredients of Ponstel and Hydroxyzine pamoate, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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