Profen vs. Gralise: side effect and effectiveness comparison - a phase IV clinical study
We compare the side effects and drug effectiveness of Profen and Gralise. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 663,784 people who take Profen and Gralise, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
663,784 people who take Profen and Gralise are studied.
What is Profen?
Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 210,482 Profen users for its effectiveness, alternative drugs and more.
What is Gralise?
Gralise has active ingredients of gabapentin. It is often used in neuralgia. eHealthMe is studying from 4,176 Gralise users for its effectiveness, alternative drugs and more.
Number of reports submitted per year:
Drugs being compared in this study:
- Gralise (gabapentin)
- Profen (ibuprofen)
Most common side effects of the drugs, overall:
Most common side effects of the drugs, in long term (1+ years) use:
- not at all: 3.15 %
- somewhat: 24.36 %
- moderate: 38.07 %
- high: 26.55 %
- very high: 7.87 %
- not at all: 6.18 %
- somewhat: 29.62 %
- moderate: 36.05 %
- high: 20.71 %
- very high: 7.43 %
Want to compare Profen with Gralise?Personalize this study to your gender and age (0-99+).
How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- de Landaluce, L. O., Carbonell, P., Asensio, C., Escoda, N., López, P., & Laporte, J. R. , "Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database", Drug safety, 2018 Jan .
- Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
- Scarff JR, "The Potential for Somnambulism Associated with Gabapentin", The Internet Journal of Psychiatry, 2014 Jan .
Alternative drugs to, pros and cons of:
Common Profen side effects:
- Pain: 17,497 reports
- Fatigue (feeling of tiredness): 15,338 reports
- Drug ineffective: 14,999 reports
- Headache (pain in head): 13,179 reports
- Rashes (redness): 11,357 reports
- Joint pain: 10,715 reports
- Breathing difficulty: 10,286 reports
- Nausea and vomiting: 10,029 reports
Browse all side effects of Profen:a b c d e f g h i j k l m n o p q r s t u v w x y z
Common Gralise side effects:
- Dizziness: 357 reports
- Fatigue (feeling of tiredness): 311 reports
- Drowsiness: 291 reports
- Drug ineffective: 205 reports
- Pain: 176 reports
- Headache (pain in head): 145 reports
- Memory loss: 135 reports
Browse all side effects of Gralise:a b c d e f g h i j k l m n o p q r s t u v w x y z
How the study uses the data?
The study is based on ibuprofen and gabapentin (the active ingredients of Profen and Gralise, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Citalopram Hydrobromide and Loss Of Anatomical Alignment After Fracture Reduction - a second ago
- Tramadol Hydrochloride And Acetaminophen and Precose drug interaction - 11 seconds ago
- Nitro-Dur and Dexamethasone Acetate drug interaction - 16 seconds ago
- Istodax and Blindness - 17 seconds ago
- Pantoprazole and Detrol drug interaction - 18 seconds ago
- Epipen and Chapped Lips - 26 seconds ago
- Tolbutamide and Fainting - 28 seconds ago
- Theophylline and Folliculitis - 34 seconds ago
- Augmentin '125' and Pyogenic Granuloma - 35 seconds ago
- Paclitaxel and Nosocomial Infection - 46 seconds ago