Pyridium vs. Elmiron: side effect and effectiveness comparison - a phase IV clinical study
Summary:
We compare the side effects and drug effectiveness of Pyridium and Elmiron. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 12,183 people who take Pyridium and Elmiron, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
12,183 people who take Pyridium and Elmiron are studied.
What is Pyridium?
Pyridium has active ingredients of phenazopyridine hydrochloride. It is often used in urinary tract infection. eHealthMe is studying from 1,628 Pyridium users for its effectiveness, alternative drugs and more.
What is Elmiron?
Elmiron has active ingredients of pentosan polysulfate sodium. It is often used in interstitial cystitis (ic). eHealthMe is studying from 6,921 Elmiron users for its effectiveness, alternative drugs and more.
Number of reports submitted per year:

Drugs being compared in this study:
- Elmiron (pentosan polysulfate sodium)
- Pyridium (phenazopyridine hydrochloride)
Most common side effects of the drugs, overall:
Most common side effects of the drugs, in long term (1+ years) use:
Drug effectiveness:
Pyridium:
- not at all: 5.95 %
- somewhat: 20.83 %
- moderate: 42.26 %
- high: 22.02 %
- very high: 8.93 %
Elmiron:
- not at all: 5.83 %
- somewhat: 34.98 %
- moderate: 23.77 %
- high: 22.42 %
- very high: 13.0 %
Want to compare Pyridium with Elmiron?
Personalize this study to your gender and age (0-99+).How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
Alternative drugs to, pros and cons of:
Common Pyridium side effects:
- Urinary tract infection: 170 reports
- Fatigue (feeling of tiredness): 138 reports
- Pain: 136 reports
Browse all side effects of Pyridium:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Elmiron side effects:
- Pain: 415 reports
- Macular degeneration (painless eye condition that leads to the gradual loss of central vision): 352 reports
- Drug ineffective: 345 reports
- Diarrhea: 323 reports
- Headache (pain in head): 289 reports
Browse all side effects of Elmiron:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study is based on phenazopyridine hydrochloride and pentosan polysulfate sodium (the active ingredients of Pyridium and Elmiron, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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