Rozerem vs. Hydroxyzine hydrochloride: side effect and effectiveness comparison - a phase IV clinical study
Summary:
We compare the side effects and drug effectiveness of Rozerem and Hydroxyzine hydrochloride. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 80,022 people who take Rozerem and Hydroxyzine hydrochloride, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
80,022 people who take Rozerem and Hydroxyzine hydrochloride are studied.
What is Rozerem?
Rozerem has active ingredients of ramelteon. It is often used in insomnia. eHealthMe is studying from 7,097 Rozerem users for its effectiveness, alternative drugs and more.
What is Hydroxyzine hydrochloride?
Hydroxyzine hydrochloride has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 5,890 Hydroxyzine hydrochloride users for its effectiveness, alternative drugs and more.
Number of reports submitted per year:

Drugs being compared in this study:
- Hydroxyzine Hydrochloride (hydroxyzine hydrochloride)
- Rozerem (ramelteon)
Most common side effects of the drugs, overall:
Most common side effects of the drugs, in long term (1+ years) use:
Drug effectiveness:
Rozerem:
- not at all: 18.75 %
- somewhat: 25.89 %
- moderate: 33.04 %
- high: 18.75 %
- very high: 3.5700000000000003 %
Hydroxyzine Hydrochloride:
- not at all: 5.61 %
- somewhat: 28.05 %
- moderate: 35.01 %
- high: 22.78 %
- very high: 8.56 %
Want to compare Rozerem with Hydroxyzine hydrochloride?
Personalize this study to your gender and age (0-99+).How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Ate? ?, Arikan MF, Kaplan M, Altay M, "Hydroxyzine induced pancytopenia and petechial rashes: a rare complication", Journal Of Contemporary Medicine, 2017 Jan .
Related studies
Alternative drugs to, pros and cons of:
- Rozerem (6,907 reports)
- Hydroxyzine hydrochloride (5,495 reports)
Common Rozerem side effects:
- Drug ineffective: 889 reports
- Drowsiness: 468 reports
- Insomnia (sleeplessness): 430 reports
- Dizziness: 330 reports
Browse all side effects of Rozerem:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Hydroxyzine hydrochloride side effects:
- Rashes (redness): 408 reports
- Fatigue (feeling of tiredness): 389 reports
- Itching: 357 reports
- Headache (pain in head): 318 reports
- Pain: 300 reports
- Fever: 273 reports
- Diarrhea: 264 reports
- Dizziness: 252 reports
Browse all side effects of Hydroxyzine hydrochloride:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study is based on ramelteon and hydroxyzine hydrochloride (the active ingredients of Rozerem and Hydroxyzine hydrochloride, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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