Sumatriptan vs. Zolmitriptan: side effect and effectiveness comparison - a phase IV clinical study
Summary:
We compare the side effects and drug effectiveness of Sumatriptan and Zolmitriptan. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 42,382 people who take Sumatriptan and Zolmitriptan, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
42,382 people who take Sumatriptan and Zolmitriptan are studied.
What is Sumatriptan?
Sumatriptan has active ingredients of sumatriptan succinate. It is often used in migraine. eHealthMe is studying from 12,911 Sumatriptan users for its effectiveness, alternative drugs and more.
What is Zolmitriptan?
Zolmitriptan has active ingredients of zolmitriptan. It is often used in migraine. eHealthMe is studying from 1,920 Zolmitriptan users for its effectiveness, alternative drugs and more.
Number of reports submitted per year:
Drugs being compared in this study:
- Zolmitriptan (zolmitriptan)
- Sumatriptan (sumatriptan succinate)
Most common side effects of the drugs, overall:
Most common side effects of the drugs, in long term (1+ years) use:
Drug effectiveness:
Sumatriptan:
- not at all: 1.79 %
- somewhat: 12.31 %
- moderate: 22.83 %
- high: 35.22 %
- very high: 27.85 %
Zolmitriptan:
- not at all: 2.49 %
- somewhat: 10.79 %
- moderate: 17.84 %
- high: 36.51 %
- very high: 32.37 %
Want to compare Sumatriptan with Zolmitriptan?
Personalize this study to your gender and age (0-99+).How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
Alternative drugs to, pros and cons of:
- Sumatriptan (12,011 reports)
- Zolmitriptan (1,889 reports)
Common Sumatriptan side effects:
- Abdominal discomfort: 142 reports
- Abdominal pain: 225 reports
- Abdominal pain upper: 148 reports
- Acute kidney failure: 124 reports
- Anaemia (lack of blood): 116 reports
- Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat): 117 reports
- Asthma: 189 reports
- Back pain: 181 reports
- Breathing difficulty: 458 reports
- Chest pain: 456 reports
- Chills (felling of cold): 104 reports
- Chronic kidney disease: 215 reports
- Confusional state: 178 reports
- Constipation: 137 reports
- Cough: 143 reports
- C-reactive protein increased: 102 reports
- Deep venous thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 107 reports
- Depression: 394 reports
- Diarrhea: 397 reports
- Dizziness: 588 reports
- Drowsiness: 308 reports
- Drug hypersensitivity: 266 reports
- Drug ineffective: 1,817 reports
- Drug intolerance (drug sensitivity): 247 reports
- Emotional distress: 124 reports
- Fall: 292 reports
- Fatigue (feeling of tiredness): 730 reports
- Fever: 245 reports
- Gait disturbance: 123 reports
- Gastroesophageal reflux disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 151 reports
- Hair loss: 137 reports
- Headache (pain in head): 947 reports
- Head injury: 181 reports
- Heart palpitations (feelings or sensations that your heart is pounding or racing): 164 reports
- High blood pressure: 517 reports
- Hot flush (sudden feelings of heat): 171 reports
- Hyperhidrosis (abnormally increased sweating): 212 reports
- Hypersensitivity: 150 reports
- Hypoaesthesia (reduced sense of touch or sensation): 282 reports
- Hypotension (abnormally low blood pressure): 181 reports
- Injection site pain: 238 reports
- Injury: 112 reports
- Insomnia (sleeplessness): 247 reports
- Itching: 212 reports
- Joint pain: 378 reports
- Joint swelling: 138 reports
- Loss of consciousness: 159 reports
- Malaise (a feeling of general discomfort or uneasiness): 377 reports
- Memory loss: 272 reports
- Migraine (headache): 1,049 reports
- Muscle aches (muscle pain): 132 reports
- Muscle spasms (muscle contraction): 186 reports
- Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 104 reports
- Nausea (feeling of having an urge to vomit): 940 reports
- Nausea and vomiting: 489 reports
- Neck pain: 118 reports
- Oedema peripheral (superficial swelling): 109 reports
- Overdose: 137 reports
- Pain: 666 reports
- Pain in extremity: 229 reports
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 258 reports
- Pneumonia: 166 reports
- Psoriasis (immune-mediated disease that affects the skin): 136 reports
- Pulmonary embolism (blockage of the main artery of the lung): 112 reports
- Rashes (redness): 299 reports
- Sinusitis (inflammation of sinus): 157 reports
- Skin blushing/flushing (a sudden reddening of the face, neck): 152 reports
- Stress and anxiety: 591 reports
- Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 102 reports
- Suicidal ideation: 140 reports
- Therapeutic response decreased (less preventive response): 148 reports
- Throat tightness: 109 reports
- Tremor (trembling or shaking movements in one or more parts of your body): 235 reports
- Urinary tract infection: 183 reports
- Urticaria (rash of round, red welts on the skin that itch intensely): 114 reports
- Vision blurred: 134 reports
- Weakness: 332 reports
- Weight decreased: 262 reports
- Weight increased: 199 reports
Common Zolmitriptan side effects:
- Diarrhea: 109 reports
- Dizziness: 110 reports
- Drug ineffective: 160 reports
- Fatigue (feeling of tiredness): 166 reports
- Headache (pain in head): 229 reports
- Migraine (headache): 212 reports
- Nausea (feeling of having an urge to vomit): 231 reports
- Nausea and vomiting: 106 reports
- Pain: 139 reports
- Weakness: 109 reports
How the study uses the data?
The study is based on sumatriptan succinate and zolmitriptan (the active ingredients of Sumatriptan and Zolmitriptan, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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