Vasotec vs. Lexapro: side effect and effectiveness comparison - a phase IV clinical study
Summary:
We compare the side effects and drug effectiveness of Vasotec and Lexapro. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 228,428 people who take Vasotec and Lexapro, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
228,428 people who take Vasotec and Lexapro are studied.
What is Vasotec?
Vasotec has active ingredients of enalapril maleate. It is often used in high blood pressure. eHealthMe is studying from 14,643 Vasotec users for its effectiveness, alternative drugs and more.
What is Lexapro?
Lexapro has active ingredients of escitalopram oxalate. It is often used in depression. eHealthMe is studying from 84,135 Lexapro users for its effectiveness, alternative drugs and more.
Number of reports submitted per year:

Drugs being compared in this study:
- Vasotec (enalapril maleate)
- Lexapro (escitalopram oxalate)
Most common side effects of the drugs, overall:
Most common side effects of the drugs, in long term (1+ years) use:
Drug effectiveness:
Vasotec:
- not at all: 1.32 %
- somewhat: 13.44 %
- moderate: 36.36 %
- high: 36.1 %
- very high: 12.78 %
Lexapro:
- not at all: 4.06 %
- somewhat: 19.38 %
- moderate: 36.79 %
- high: 29.74 %
- very high: 10.03 %
Want to compare Vasotec with Lexapro?
Personalize this study to your gender and age (0-99+).How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
Related studies
Alternative drugs to, pros and cons of:
Common Vasotec side effects:
- Weakness: 1,011 reports
- Chest pain: 919 reports
- Fatigue (feeling of tiredness): 862 reports
- Pain: 849 reports
- High blood pressure: 820 reports
- Heart attack: 801 reports
Browse all side effects of Vasotec:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Lexapro side effects:
- Fatigue (feeling of tiredness): 6,469 reports
- Stress and anxiety: 5,849 reports
- Pain: 5,093 reports
- Depression: 5,063 reports
- Headache (pain in head): 4,584 reports
- Drug ineffective: 4,383 reports
- Dizziness: 4,332 reports
Browse all side effects of Lexapro:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study is based on enalapril maleate and escitalopram oxalate (the active ingredients of Vasotec and Lexapro, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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