Vitamin b2 vs. Profen: side effect and effectiveness comparison - a phase IV clinical study
Summary:
We compare the side effects and drug effectiveness of Vitamin b2 and Profen. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 313,006 people who take Vitamin b2 and Profen, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
313,006 people who take Vitamin b2 and Profen are studied.
What is Vitamin b2?
Vitamin b2 has active ingredients of riboflavin. It is often used in migraine. eHealthMe is studying from 1,340 Vitamin b2 users for its effectiveness, alternative drugs and more.
What is Profen?
Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 210,482 Profen users for its effectiveness, alternative drugs and more.
Number of reports submitted per year:

Drugs being compared in this study:
- Vitamin B2 (riboflavin)
- Profen (ibuprofen)
Most common side effects of the drugs, overall:
Most common side effects of the drugs, in long term (1+ years) use:
Drug effectiveness:
Vitamin B2:
- not at all: 6.74 %
- somewhat: 30.34 %
- moderate: 42.7 %
- high: 11.24 %
- very high: 8.99 %
Profen:
- not at all: 3.14 %
- somewhat: 24.43 %
- moderate: 38.27 %
- high: 26.27 %
- very high: 7.89 %
Want to compare Vitamin b2 with Profen?
Personalize this study to your gender and age (0-99+).How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
Related studies
Alternative drugs to, pros and cons of:
- Vitamin b2 (1,203 reports)
- Profen (204,735 reports)
Common Vitamin b2 side effects:
- Fatigue (feeling of tiredness): 174 reports
- Headache (pain in head): 155 reports
- Drug ineffective: 148 reports
- Dizziness: 106 reports
Browse all side effects of Vitamin b2:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Profen side effects:
- Pain: 17,497 reports
- Fatigue (feeling of tiredness): 15,338 reports
- Drug ineffective: 14,999 reports
- Headache (pain in head): 13,179 reports
- Rashes (redness): 11,357 reports
- Breathing difficulty: 10,787 reports
- Joint pain: 10,715 reports
Browse all side effects of Profen:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study is based on riboflavin and ibuprofen (the active ingredients of Vitamin b2 and Profen, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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