Zenatane vs. Oxytetracycline hydrochloride: side effect and effectiveness comparison - a phase IV clinical study
Summary:
We compare the side effects and drug effectiveness of Zenatane and Oxytetracycline hydrochloride. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 67,376 people who take Zenatane and Oxytetracycline hydrochloride, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
67,376 people who take Zenatane and Oxytetracycline hydrochloride are studied.
What is Zenatane?
Zenatane has active ingredients of isotretinoin. It is often used in acne. eHealthMe is studying from 4,443 Zenatane users for its effectiveness, alternative drugs and more.
What is Oxytetracycline hydrochloride?
Oxytetracycline hydrochloride has active ingredients of oxytetracycline hydrochloride. It is often used in rosacea. eHealthMe is studying from 67 Oxytetracycline hydrochloride users for its effectiveness, alternative drugs and more.
Number of reports submitted per year:

Drugs being compared in this study:
- Oxytetracycline Hydrochloride (oxytetracycline hydrochloride)
- Zenatane (isotretinoin)
Most common side effects of the drugs, overall:
Most common side effects of the drugs, in long term (1+ years) use:
Drug effectiveness:
Zenatane:
- not at all: 3.44 %
- somewhat: 13.91 %
- moderate: 24.96 %
- high: 37.97 %
- very high: 19.72 %
Oxytetracycline Hydrochloride:
- not at all: 0 %
- somewhat: 17.24 %
- moderate: 44.83 %
- high: 31.03 %
- very high: 6.9 %
Want to compare Zenatane with Oxytetracycline hydrochloride?
Personalize this study to your gender and age (0-99+).How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Ersoy MA, Ersoy HT, "Manic symptoms associated with isotretinoin and methylphenidate combination: a case report", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2014 Sep .
Related studies
Alternative drugs to, pros and cons of:
- Zenatane (4,438 reports)
- Oxytetracycline hydrochloride (27 reports)
Common Zenatane side effects:
- Depression: 325 reports
- Mood swings (an extreme or rapid change in mood): 229 reports
- Headache (pain in head): 224 reports
- Joint pain: 206 reports
- Dry skin: 195 reports
- High blood cholesterol: 159 reports
- Drug ineffective: 152 reports
- Stress and anxiety: 124 reports
Browse all side effects of Zenatane:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study is based on isotretinoin and oxytetracycline hydrochloride (the active ingredients of Zenatane and Oxytetracycline hydrochloride, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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