Constipation and drugs of ingredients of 5 - htp - a phase IV clinical study of FDA data


Constipation is found among people who take drugs with ingredients of 5 - htp, especially for people who are female, 60+ old . This phase IV clinical study is created by eHealthMe based on reports of 619 people who have side effects when taking drugs with ingredients of 5 - htp from the FDA, and is updated regularly.

Drug(s) considered in the study (i.e. both brand name and generic drugs): 5 htp, 5-hydroxy l-tryptophan, 5-hydroxy tryptophan, 5-l-hydroxytryptophan, L-5 htp, L-5 hydroxytryptophan, Oxitriptan.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Jun, 01, 2023

619 people reported to have side effects when taking drugs with ingredients of 5 - htp.
Among them, 15 people (2.42%) have Constipation

What is Constipation?

Constipation is found to be associated with 4,489 drugs and 4,374 conditions by eHealthMe.

Number of reports submitted per year:

Could drugs with ingredients of 5 - htp cause Constipation?

Gender of people who have Constipation when taking drugs with ingredients of 5 - htp *:

  • female: 78.57 %
  • male: 21.43 %

Age of people who have Constipation when taking drugs with ingredients of 5 - htp *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 14.29 %
  • 30-39: 14.29 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 71.43 %

Conditions people have *:

  1. Migraine (headache): 6 people, 40.00%
  2. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 3 people, 20.00%
  3. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 20.00%
  4. Psoriasis (immune-mediated disease that affects the skin): 2 people, 13.33%
  5. High Blood Pressure: 2 people, 13.33%
  6. Sleep Disorder: 1 person, 6.67%
  7. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 6.67%
  8. Gout (uric acid crystals building up in the body): 1 person, 6.67%
  9. Fatigue (feeling of tiredness): 1 person, 6.67%
  10. Enlarged Prostate: 1 person, 6.67%

Other drugs people take *:

  1. Magnesium: 7 people, 46.67%
  2. Aimovig: 6 people, 40.00%
  3. Potassium: 4 people, 26.67%
  4. Dyazide: 3 people, 20.00%
  5. Eliquis: 3 people, 20.00%
  6. Vitamin D: 2 people, 13.33%
  7. Vitamin C: 2 people, 13.33%
  8. Lantus: 2 people, 13.33%
  9. Melatonin: 2 people, 13.33%
  10. Cymbalta: 2 people, 13.33%

Other side effects people have besides Constipation *:

  1. Migraine (headache): 4 people, 26.67%
  2. Fatigue (feeling of tiredness): 4 people, 26.67%
  3. Weakness: 4 people, 26.67%
  4. Nausea (feeling of having an urge to vomit): 4 people, 26.67%
  5. Pain: 3 people, 20.00%
  6. Abdominal Pain Upper: 3 people, 20.00%
  7. Blood Potassium Decreased: 3 people, 20.00%
  8. Breathing Difficulty: 3 people, 20.00%
  9. Hair Loss: 3 people, 20.00%
  10. Hypertensive Crisis: 3 people, 20.00%

* Approximation only. Some reports may have incomplete information.

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Drugs with ingredients of 5 - htp, their effectiveness, alternatives and more:

How the study uses the data?

The study uses data from the FDA. It is based on 5 - htp. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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