Ototoxicity and drugs of ingredients of acetaminophen; codeine phosphate - a phase IV clinical study of FDA data


Summary:

Ototoxicity is reported only by a few people who take drugs with ingredients of acetaminophen; codeine phosphate. This phase IV clinical study analyzes 40,390 people who have side effects while taking drugs with ingredients of acetaminophen; codeine phosphate from the the FDA. Among them, 4 have Ototoxicity. Find out below who they are, when they have Ototoxicity and more.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Acetaminophen and codeine phosphate, Capital and codeine, Co-codamol, Codrix, Empracet w/ codeine phosphate #3, Empracet w/ codeine phosphate #4, Papa-deine #3, Papa-deine #4, Phenaphen w/ codeine no. 2, Phenaphen w/ codeine no. 3, Phenaphen w/ codeine no. 4, Phenaphen-650 w/ codeine, Proval #3, Tylenol w/ codeine, Tylenol w/ codeine no. 1, Tylenol w/ codeine no. 2, Tylenol w/ codeine no. 3, Tylenol w/ codeine no. 4.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.


On Sep, 25, 2022

40,390 people reported to have side effects when taking drugs with ingredients of acetaminophen; codeine phosphate.
Among them, 4 people (0.01%) have Ototoxicity


What is Ototoxicity?

Ototoxicity (damage to the ear) is found to be associated with 607 drugs and 341 conditions by eHealthMe.

Number of reports submitted per year:

Could drugs with ingredients of acetaminophen; codeine phosphate cause Ototoxicity?

Gender of people who have Ototoxicity when taking drugs with ingredients of acetaminophen; codeine phosphate *:

  • female: 75 %
  • male: 25 %

Age of people who have Ototoxicity when taking drugs with ingredients of acetaminophen; codeine phosphate *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 33.33 %
  • 50-59: 0.0 %
  • 60+: 66.67 %

Conditions people have *:

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 25.00%
  2. Prostatitis (inflammation of the prostate gland): 1 person, 25.00%
  3. Cervicobrachial Syndrome (pain in neck and arm with changing location): 1 person, 25.00%

Other drugs people take *:

  1. Vicoprofen: 1 person, 25.00%
  2. Vicodin Es: 1 person, 25.00%
  3. Leflunomide: 1 person, 25.00%
  4. Lansoprazole: 1 person, 25.00%
  5. Lactulose: 1 person, 25.00%
  6. Ibuprofen: 1 person, 25.00%
  7. Furosemide: 1 person, 25.00%
  8. Folic Acid: 1 person, 25.00%
  9. Fluoxetine Hydrochloride: 1 person, 25.00%
  10. Fentanyl Citrate: 1 person, 25.00%

Other side effects people have besides Ototoxicity *:

  1. Joint Pain: 2 people, 50.00%
  2. Confusional State: 2 people, 50.00%
  3. Diarrhea: 2 people, 50.00%
  4. Pain In Extremity: 2 people, 50.00%
  5. Gait Disturbance: 2 people, 50.00%
  6. Dizziness: 2 people, 50.00%
  7. Balance Disorder: 2 people, 50.00%
  8. Stress And Anxiety: 2 people, 50.00%
  9. Weakness: 2 people, 50.00%
  10. Tinnitus (a ringing in the ears): 2 people, 50.00%

* Approximation only. Some reports may have incomplete information.


How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; codeine phosphate. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe: