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Blood folate decreased and drugs of ingredients of amlodipine besylate - a phase IV clinical study of FDA data


Summary:

Blood folate decreased is found among people who take drugs with ingredients of amlodipine besylate, especially for people who are female, 60+ old , have been taking the drugs for 6 - 12 months. This phase IV clinical study is created by eHealthMe based on reports of 408,933 people who have side effects when taking drugs with ingredients of amlodipine besylate from the FDA, and is updated regularly.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Amlodipine, Amlodipine besylate, Norliqva, Norvasc.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Mar, 21, 2023

408,933 people reported to have side effects when taking drugs with ingredients of amlodipine besylate.
Among them, 21 people (0.01%) have Blood folate decreased

What is Blood folate decreased?

Blood folate decreased is found to be associated with 431 drugs and 215 conditions by eHealthMe.

Number of reports submitted per year:

Could drugs with ingredients of amlodipine besylate cause Blood folate decreased?

Time on drugs with ingredients of amlodipine besylate when people have Blood folate decreased *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 100 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Blood folate decreased when taking drugs with ingredients of amlodipine besylate *:

  • female: 71.43 %
  • male: 28.57 %

Age of people who have Blood folate decreased when taking drugs with ingredients of amlodipine besylate *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 6.25 %
  • 30-39: 0.0 %
  • 40-49: 25.0 %
  • 50-59: 18.75 %
  • 60+: 50.0 %

Conditions people have *:

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 14.29%
  2. Multiple Myeloma (cancer of the plasma cells): 3 people, 14.29%
  3. High Blood Cholesterol: 2 people, 9.52%
  4. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 9.52%
  5. Heart Rate Irregular: 1 person, 4.76%
  6. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 4.76%
  7. Barrett's Oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach): 1 person, 4.76%
  8. Blood Iron Decreased: 1 person, 4.76%
  9. Blood Pressure Fluctuation: 1 person, 4.76%
  10. Cardiac Disorder: 1 person, 4.76%

Other drugs people take *:

  1. Magnesium: 5 people, 23.81%
  2. Potassium: 3 people, 14.29%
  3. Pepcid: 3 people, 14.29%
  4. Revlimid: 3 people, 14.29%
  5. Furosemide: 3 people, 14.29%
  6. Zithromax: 2 people, 9.52%
  7. Xanax: 2 people, 9.52%
  8. Micardis: 2 people, 9.52%
  9. Mevacor: 2 people, 9.52%
  10. Lipitor: 2 people, 9.52%

Other side effects people have besides Blood folate decreased *:

  1. Fatigue (feeling of tiredness): 6 people, 28.57%
  2. Fever: 5 people, 23.81%
  3. Nausea (feeling of having an urge to vomit): 5 people, 23.81%
  4. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 4 people, 19.05%
  5. Haemoglobin Decreased: 4 people, 19.05%
  6. White Blood Cell Count Decreased: 4 people, 19.05%
  7. Pain: 4 people, 19.05%
  8. Cough: 4 people, 19.05%
  9. Weight Decreased: 4 people, 19.05%
  10. Vitamin B12 Decreased: 3 people, 14.29%

* Approximation only. Some reports may have incomplete information.

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Drugs with ingredients of amlodipine besylate, their effectiveness, alternatives and more:

How the study uses the data?

The study uses data from the FDA. It is based on amlodipine besylate. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

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DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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