Itching and drugs of ingredients of amphotericin b - a phase IV clinical study of FDA data


Summary:

Itching is found among people who take drugs with ingredients of amphotericin b, especially for people who are female, 60+ old , have been taking the drugs for < 1 month. This phase IV clinical study is created by eHealthMe based on reports of 27,924 people who have side effects when taking drugs with ingredients of amphotericin b from the FDA, and is updated regularly.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Abelcet, Ambisome, Amphotec, Amphotericin b, Fungizone.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.


On Oct, 01, 2022

27,924 people reported to have side effects when taking drugs with ingredients of amphotericin b.
Among them, 312 people (1.12%) have Itching


What is Itching?

Itching is found to be associated with 4,194 drugs and 4,255 conditions by eHealthMe.

Number of reports submitted per year:

Could drugs with ingredients of amphotericin b cause Itching?

Time on drugs with ingredients of amphotericin b when people have Itching *:

  • < 1 month: 90 %
  • 1 - 6 months: 10 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Itching when taking drugs with ingredients of amphotericin b *:

  • female: 55.26 %
  • male: 44.74 %

Age of people who have Itching when taking drugs with ingredients of amphotericin b *:

  • 0-1: 0.38 %
  • 2-9: 9.06 %
  • 10-19: 3.02 %
  • 20-29: 6.42 %
  • 30-39: 16.6 %
  • 40-49: 16.6 %
  • 50-59: 17.36 %
  • 60+: 30.57 %

Conditions people have *:

  1. High Blood Pressure: 23 people, 7.37%
  2. Constipation: 21 people, 6.73%
  3. Pain: 20 people, 6.41%
  4. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 20 people, 6.41%
  5. Hyperuricaemia (level of uric acid in the blood that is abnormally high): 16 people, 5.13%
  6. Nausea (feeling of having an urge to vomit): 15 people, 4.81%
  7. Disseminated Cryptococcosis (one of the acquired immune deficiency syndrome defining criteria and the most common cause of life threatening meningitis): 14 people, 4.49%
  8. High Blood Cholesterol: 13 people, 4.17%
  9. Pneumonia: 12 people, 3.85%
  10. Diabetes: 12 people, 3.85%

Other drugs people take *:

  1. Vancomycin: 62 people, 19.87%
  2. Diflucan: 47 people, 15.06%
  3. Lasix: 43 people, 13.78%
  4. Neupogen: 40 people, 12.82%
  5. Allopurinol: 37 people, 11.86%
  6. Zofran: 30 people, 9.62%
  7. Zovirax: 27 people, 8.65%
  8. Paracetamol: 25 people, 8.01%
  9. Imodium: 25 people, 8.01%
  10. Isoptin: 25 people, 8.01%

Other side effects people have besides Itching *:

  1. Rashes (redness): 125 people, 40.06%
  2. Fever: 99 people, 31.73%
  3. Pain: 53 people, 16.99%
  4. Erythema Multiforme (a type of hypersensitivity reaction): 45 people, 14.42%
  5. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure): 44 people, 14.10%
  6. Nausea And Vomiting: 43 people, 13.78%
  7. Nausea (feeling of having an urge to vomit): 42 people, 13.46%
  8. Fatigue (feeling of tiredness): 31 people, 9.94%
  9. Diarrhea: 29 people, 9.29%
  10. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 27 people, 8.65%

* Approximation only. Some reports may have incomplete information.


How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Drugs with ingredients of amphotericin b, their effectiveness, alternatives and more:

How the study uses the data?

The study uses data from the FDA. It is based on amphotericin b. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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