Multiple sclerosis and drugs of ingredients of buprenorphine hydrochloride; naloxone hydrochloride - a phase IV clinical study of FDA data
Multiple sclerosis is found among people who take drugs with ingredients of buprenorphine hydrochloride; naloxone hydrochloride, especially for people who are female, 30-39 old , have been taking the drugs for < 1 month. This phase IV clinical study is created by eHealthMe based on reports of 32,222 people who have side effects when taking drugs with ingredients of buprenorphine hydrochloride; naloxone hydrochloride from the FDA, and is updated regularly.
Drug(s) considered in the study (i.e. both brand name and generic drugs): Bunavail, Buprenorphine hydrochloride and naloxone hydrochloride, Buprenorphine hydrochloride; naloxone hydrochloride, Cassipa, Suboxone, Zubsolv.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
32,222 people reported to have side effects when taking drugs with ingredients of buprenorphine hydrochloride; naloxone hydrochloride.
Among them, 32 people (0.1%) have Multiple sclerosis
What is Multiple sclerosis?
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath) is found to be associated with 2,111 drugs and 1,306 conditions by eHealthMe.
Number of reports submitted per year:
Time on drugs with ingredients of buprenorphine hydrochloride; naloxone hydrochloride when people have Multiple sclerosis *:
- < 1 month: 50 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 50 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
Gender of people who have Multiple sclerosis when taking drugs with ingredients of buprenorphine hydrochloride; naloxone hydrochloride *:
- female: 73.33 %
- male: 26.67 %
Age of people who have Multiple sclerosis when taking drugs with ingredients of buprenorphine hydrochloride; naloxone hydrochloride *:
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 18.18 %
- 30-39: 59.09 %
- 40-49: 13.64 %
- 50-59: 9.09 %
- 60+: 0.0 %
Conditions people have *:
- Drug Dependence: 7 people, 21.88%
- Pain: 4 people, 12.50%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 9.38%
- Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 3 people, 9.38%
- Depression: 3 people, 9.38%
- Urinary Incontinence (inability to control the flow of urine and involuntary urination): 2 people, 6.25%
- Migraine (headache): 2 people, 6.25%
- Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 1 person, 3.12%
- High Blood Cholesterol: 1 person, 3.12%
- Herpes Simplex (herpes simplex is a common viral infection): 1 person, 3.12%
Other drugs people take *:
- Benadryl: 6 people, 18.75%
- Tylenol: 5 people, 15.62%
- Gravol: 3 people, 9.38%
- Rebif: 3 people, 9.38%
- Zofran: 2 people, 6.25%
- Myrbetriq: 2 people, 6.25%
- Flonase: 2 people, 6.25%
- Subutex: 2 people, 6.25%
- Tysabri: 2 people, 6.25%
- Vesicare: 2 people, 6.25%
Other side effects people have besides Multiple sclerosis *:
- Fatigue (feeling of tiredness): 11 people, 34.38%
- Stress And Anxiety: 8 people, 25.00%
- Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 5 people, 15.62%
- Pain: 5 people, 15.62%
- Dental Caries: 5 people, 15.62%
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 5 people, 15.62%
- Balance Disorder: 5 people, 15.62%
- Blindness: 5 people, 15.62%
- Nausea And Vomiting: 5 people, 15.62%
- Drowsiness: 4 people, 12.50%
* Approximation only. Some reports may have incomplete information.
How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Christopher KL, Elner VM, Demirci H, "Conjunctival Lymphoma in a Patient on Fingolimod for Relapsing-Remitting Multiple Sclerosis", Ophthalmic Plastic & Reconstructive Surgery, 2017 May .
- Christopher, K. L., Elner, V. M., & Demirci, H. , "Conjunctival lymphoma in a patient on fingolimod for relapsing-remitting multiple sclerosis", Ophthalmic plastic and reconstructive surgery , 2014 Jan .
Drugs with ingredients of buprenorphine hydrochloride; naloxone hydrochloride, their effectiveness, alternatives and more:
How the study uses the data?
The study uses data from the FDA. It is based on buprenorphine hydrochloride; naloxone hydrochloride. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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