Gastrointestinal inflammation and drugs of ingredients of carbamazepine - a phase IV clinical study of FDA data


Summary:

Gastrointestinal inflammation is found among people who take drugs with ingredients of carbamazepine, especially for people who are male, 60+ old , have been taking the drugs for < 1 month. This phase IV clinical study is created by eHealthMe based on reports of 81,611 people who have side effects when taking drugs with ingredients of carbamazepine from the FDA, and is updated regularly.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Carbamazepine, Carbatrol, Carnexiv, Epitol, Equetro, Tegretol, Tegretol-xr, Teril.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.


On Oct, 03, 2022

81,611 people reported to have side effects when taking drugs with ingredients of carbamazepine.
Among them, 7 people (0.01%) have Gastrointestinal inflammation


What is Gastrointestinal inflammation?

Gastrointestinal inflammation (inflammation of stomach and intestine) is found to be associated with 823 drugs and 517 conditions by eHealthMe.

Number of reports submitted per year:

Could drugs with ingredients of carbamazepine cause Gastrointestinal inflammation?

Time on drugs with ingredients of carbamazepine when people have Gastrointestinal inflammation *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Gastrointestinal inflammation when taking drugs with ingredients of carbamazepine *:

  • female: 28.57 %
  • male: 71.43 %

Age of people who have Gastrointestinal inflammation when taking drugs with ingredients of carbamazepine *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 25 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 75 %

Conditions people have *:

  1. Diabetes: 3 people, 42.86%
  2. Tremor (trembling or shaking movements in one or more parts of your body): 2 people, 28.57%
  3. Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 2 people, 28.57%
  4. Cardiac Disorder: 2 people, 28.57%
  5. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 14.29%
  6. Pain: 1 person, 14.29%
  7. Hiv Infection: 1 person, 14.29%
  8. Emotional Disorder: 1 person, 14.29%
  9. Depression: 1 person, 14.29%
  10. Crohn's Disease (condition that causes inflammation of the gastrointestinal tract): 1 person, 14.29%

Other drugs people take *:

  1. Methotrexate: 2 people, 28.57%
  2. Lantus: 2 people, 28.57%
  3. Humira: 2 people, 28.57%
  4. Acetylsalicylic Acid: 2 people, 28.57%
  5. Viread: 1 person, 14.29%
  6. Tylenol: 1 person, 14.29%
  7. Remodulin: 1 person, 14.29%
  8. Lamictal: 1 person, 14.29%
  9. Klonopin: 1 person, 14.29%
  10. Kaletra: 1 person, 14.29%

Other side effects people have besides Gastrointestinal inflammation *:

  1. Flatulence (flatus expelled through the anus): 2 people, 28.57%
  2. Constipation: 2 people, 28.57%
  3. Wound Complication: 1 person, 14.29%
  4. Gastritis (inflammation of stomach): 1 person, 14.29%
  5. Enteritis (inflammation of the small intestine): 1 person, 14.29%
  6. Diarrhea: 1 person, 14.29%
  7. Death: 1 person, 14.29%
  8. Cytolytic Hepatitis (dissolution or destruction of a liver cell): 1 person, 14.29%
  9. Cutaneous Vasculitis (an inflammatory process affecting the vessel wall that leads to its damage): 1 person, 14.29%
  10. Cholecystitis (infection of gallbladder): 1 person, 14.29%

* Approximation only. Some reports may have incomplete information.


How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

Drugs with ingredients of carbamazepine, their effectiveness, alternatives and more:

How the study uses the data?

The study uses data from the FDA. It is based on carbamazepine. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe: