Dupuytren's contracture and drugs of ingredients of cephalexin - a phase IV clinical study of FDA data


Summary:

Dupuytren's contracture is found among people who take drugs with ingredients of cephalexin, especially for people who are male, 60+ old , have been taking the drugs for < 1 month. This phase IV clinical study is created by eHealthMe based on reports of 37,870 people who have side effects when taking drugs with ingredients of cephalexin from the FDA, and is updated regularly.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Cephalexin, Keflet, Keflex, Panixine disperdose.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.


On Sep, 25, 2022

37,870 people reported to have side effects when taking drugs with ingredients of cephalexin.
Among them, 14 people (0.04%) have Dupuytren's contracture


What is Dupuytren's contracture?

Dupuytren's contracture (thickening of the fibrous tissue layer underneath the skin of the palm and fingers) is found to be associated with 459 drugs and 212 conditions by eHealthMe.

Number of reports submitted per year:

Could drugs with ingredients of cephalexin cause Dupuytren's contracture?

Time on drugs with ingredients of cephalexin when people have Dupuytren's contracture *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Dupuytren's contracture when taking drugs with ingredients of cephalexin *:

  • female: 21.43 %
  • male: 78.57 %

Age of people who have Dupuytren's contracture when taking drugs with ingredients of cephalexin *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

Conditions people have *:

  1. Rash Pruritic (redness with itching): 3 people, 21.43%
  2. Osteoporosis (bones weak and more likely to break): 1 person, 7.14%
  3. Multiple Myeloma (cancer of the plasma cells): 1 person, 7.14%
  4. Lung Cancer - Non-Small Cell (lung cancer): 1 person, 7.14%
  5. Erection Problems: 1 person, 7.14%

Other drugs people take *:

  1. Lasix: 11 people, 78.57%
  2. Lisinopril: 11 people, 78.57%
  3. Pepcid: 11 people, 78.57%
  4. Prednisone: 9 people, 64.29%
  5. Zometa: 8 people, 57.14%
  6. Peridex: 8 people, 57.14%
  7. Amoxicillin: 8 people, 57.14%
  8. Aredia: 8 people, 57.14%
  9. Carvedilol: 8 people, 57.14%
  10. Celexa: 8 people, 57.14%

Other side effects people have besides Dupuytren's contracture *:

  1. Depression: 12 people, 85.71%
  2. Pain: 11 people, 78.57%
  3. Musculoskeletal Discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves): 9 people, 64.29%
  4. Swallowing Difficulty: 9 people, 64.29%
  5. Stress And Anxiety: 9 people, 64.29%
  6. Neuropathy Peripheral (surface nerve damage): 9 people, 64.29%
  7. Visual Impairment: 8 people, 57.14%
  8. Dental Caries: 8 people, 57.14%
  9. Gingival Disorder (gum disease): 8 people, 57.14%
  10. Fall: 8 people, 57.14%

* Approximation only. Some reports may have incomplete information.


How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

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Drugs with ingredients of cephalexin, their effectiveness, alternatives and more:

How the study uses the data?

The study uses data from the FDA. It is based on cephalexin. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

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DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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