Smell - impaired and drugs of ingredients of cetirizine hydrochloride - a phase IV clinical study of FDA data


Summary:

Smell - impaired is found among people who take drugs with ingredients of cetirizine hydrochloride, especially for people who are female, 50-59 old , have been taking the drugs for < 1 month. This phase IV clinical study is created by eHealthMe based on reports of 155,051 people who have side effects when taking drugs with ingredients of cetirizine hydrochloride from the FDA, and is updated regularly.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Certirizine hydrochloride, Cetirizine hydrochloride, Cetirizine hydrochloride allergy, Cetirizine hydrochloride hives, Cetirizine hydrochloride hives relief, Children's cetirizine hydrochloride allergy, Children's cetirizine hydrochloride hives relief, Children's zyrtec allergy, Children's zyrtec hives relief, Quzyttir, Zerviate, Zyrtec, Zyrtec allergy, Zyrtec hives relief.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.


On Sep, 11, 2022

155,051 people reported to have side effects when taking drugs with ingredients of cetirizine hydrochloride.
Among them, 212 people (0.14%) have Smell - impaired


What is Smell - impaired?

Smell - impaired is found to be associated with 1,511 drugs and 1,028 conditions by eHealthMe.

Number of reports submitted per year:

Could drugs with ingredients of cetirizine hydrochloride cause Smell - impaired?

Time on drugs with ingredients of cetirizine hydrochloride when people have Smell - impaired *:

  • < 1 month: 70 %
  • 1 - 6 months: 30 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Smell - impaired when taking drugs with ingredients of cetirizine hydrochloride *:

  • female: 74.13 %
  • male: 25.87 %

Age of people who have Smell - impaired when taking drugs with ingredients of cetirizine hydrochloride *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 2.4 %
  • 20-29: 6.59 %
  • 30-39: 12.57 %
  • 40-49: 7.78 %
  • 50-59: 35.93 %
  • 60+: 34.73 %

Conditions people have *:

  1. Hypersensitivity: 16 people, 7.55%
  2. Multiple Allergies (allergy to multiple agents): 12 people, 5.66%
  3. Nasopharyngitis (inflammation of the nasopharynx): 11 people, 5.19%
  4. Asthma: 11 people, 5.19%
  5. Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 9 people, 4.25%
  6. High Blood Cholesterol: 7 people, 3.30%
  7. High Blood Pressure: 7 people, 3.30%
  8. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 6 people, 2.83%
  9. Seasonal Allergy (allergic condition due to certain season): 6 people, 2.83%
  10. Bladder Cancer: 5 people, 2.36%

Other drugs people take *:

  1. Singulair: 47 people, 22.17%
  2. Spiriva: 30 people, 14.15%
  3. Breo Ellipta: 26 people, 12.26%
  4. Symbicort: 25 people, 11.79%
  5. Flonase: 21 people, 9.91%
  6. Aspirin: 12 people, 5.66%
  7. Nasonex: 12 people, 5.66%
  8. Vitamin D3: 11 people, 5.19%
  9. Albuterol: 10 people, 4.72%
  10. Vitamin D: 10 people, 4.72%

Other side effects people have besides Smell - impaired *:

  1. Ageusia (loss of taste functions of the tongue): 138 people, 65.09%
  2. Fatigue (feeling of tiredness): 45 people, 21.23%
  3. Asthma: 38 people, 17.92%
  4. High Blood Pressure: 34 people, 16.04%
  5. Oxygen Saturation Decreased: 28 people, 13.21%
  6. Malaise (a feeling of general discomfort or uneasiness): 27 people, 12.74%
  7. Productive Cough: 26 people, 12.26%
  8. Nausea (feeling of having an urge to vomit): 26 people, 12.26%
  9. Nausea And Vomiting: 23 people, 10.85%
  10. Pneumonia: 18 people, 8.49%

* Approximation only. Some reports may have incomplete information.


How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

How the study uses the data?

The study uses data from the FDA. It is based on cetirizine hydrochloride. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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