Renal abscess and drugs of ingredients of crizotinib - a phase IV clinical study of FDA data


Summary:

Renal abscess is found among people who take drugs with ingredients of crizotinib, especially for people who are female, 60+ old , have been taking the drugs for 1 - 6 months. This phase IV clinical study is created by eHealthMe based on reports of 12,704 people who have side effects when taking drugs with ingredients of crizotinib from the FDA, and is updated regularly.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Xalkori.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.


On Dec, 03, 2022

12,704 people reported to have side effects when taking drugs with ingredients of crizotinib.
Among them, 54 people (0.43%) have Renal abscess


What is Renal abscess?

Renal abscess (pus in kidney) is found to be associated with 393 drugs and 214 conditions by eHealthMe.

Number of reports submitted per year:

Could drugs with ingredients of crizotinib cause Renal abscess?

Time on drugs with ingredients of crizotinib when people have Renal abscess *:

  • < 1 month: 22.22 %
  • 1 - 6 months: 33.33 %
  • 6 - 12 months: 27.78 %
  • 1 - 2 years: 13.89 %
  • 2 - 5 years: 2.7800000000000002 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Renal abscess when taking drugs with ingredients of crizotinib *:

  • female: 80 %
  • male: 20 %

Age of people who have Renal abscess when taking drugs with ingredients of crizotinib *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 12.5 %
  • 40-49: 8.33 %
  • 50-59: 25.0 %
  • 60+: 54.17 %

Conditions people have *:

  1. Lung Cancer - Non-Small Cell (lung cancer): 30 people, 55.56%
  2. Lung Neoplasm Malignant (cancer tumour of lung): 6 people, 11.11%
  3. Lung Adenocarcinoma (a form of non-small cell lung cancer): 5 people, 9.26%
  4. Fever: 4 people, 7.41%
  5. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 5.56%
  6. Insomnia (sleeplessness): 3 people, 5.56%
  7. Constipation: 2 people, 3.70%
  8. Cough: 2 people, 3.70%
  9. Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 2 people, 3.70%
  10. High Blood Pressure: 2 people, 3.70%

Other drugs people take *:

  1. Zyprexa: 4 people, 7.41%
  2. Nexium: 3 people, 5.56%
  3. Lyrica: 3 people, 5.56%
  4. Diovan: 3 people, 5.56%
  5. Zyvox: 2 people, 3.70%
  6. Blopress: 2 people, 3.70%
  7. Acetaminophen: 2 people, 3.70%
  8. Zometa: 1 person, 1.85%
  9. Zoledronic Acid: 1 person, 1.85%
  10. Methotrexate Sodium: 1 person, 1.85%

Other side effects people have besides Renal abscess *:

  1. Pyogenic Liver Abscess (liver abscess caused by bacteria): 7 people, 12.96%
  2. Renal Cyst (kidney cyst): 5 people, 9.26%
  3. Muscle Abscess (pus in muscle): 4 people, 7.41%
  4. Anaemia (lack of blood): 4 people, 7.41%
  5. Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon): 3 people, 5.56%
  6. Leukocytosis (increased white blood cells): 2 people, 3.70%
  7. Chest Wall Abscess: 2 people, 3.70%
  8. Perinephric Collection (fluid collections surrounding a kidney): 2 people, 3.70%
  9. Fever: 2 people, 3.70%
  10. Platelet Count Increased: 2 people, 3.70%

* Approximation only. Some reports may have incomplete information.


How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Drugs with ingredients of crizotinib, their effectiveness, alternatives and more:

How the study uses the data?

The study uses data from the FDA. It is based on crizotinib. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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