Dupuytren's contracture and drugs of ingredients of cyanocobalamin - a phase IV clinical study of FDA data


Dupuytren's contracture is reported only by a few people who take drugs with ingredients of cyanocobalamin. This phase IV clinical study analyzes 6,959 people who have side effects while taking drugs with ingredients of cyanocobalamin from the the FDA. Among them, 2 have Dupuytren's contracture. Find out below who they are, when they have Dupuytren's contracture and more.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Berubigen, Betalin 12, Calomist, Cobavite, Cyanocobalamin, Dodex, Nascobal, Redisol, Rubivite, Rubramin pc, Ruvite, Vi-twel, Vibisone.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 30, 2022

6,959 people reported to have side effects when taking drugs with ingredients of cyanocobalamin.
Among them, 2 people (0.03%) have Dupuytren's contracture

What is Dupuytren's contracture?

Dupuytren's contracture (thickening of the fibrous tissue layer underneath the skin of the palm and fingers) is found to be associated with 460 drugs and 212 conditions by eHealthMe.

Number of reports submitted per year:

Could drugs with ingredients of cyanocobalamin cause Dupuytren's contracture?

Gender of people who have Dupuytren's contracture when taking drugs with ingredients of cyanocobalamin *:

  • female: 0.0 %
  • male: 100 %

Age of people who have Dupuytren's contracture when taking drugs with ingredients of cyanocobalamin *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 100 %
  • 60+: 0.0 %

Conditions people have *:

  1. Septic Shock (shock due to blood infection): 1 person, 50.00%
  2. Osteoporosis (bones weak and more likely to break): 1 person, 50.00%
  3. Osteopenia (a condition where bone mineral density is lower than normal): 1 person, 50.00%
  4. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 50.00%

Other drugs people take *:

  1. Ubidecarenone: 1 person, 50.00%
  2. Synthroid: 1 person, 50.00%
  3. Prevacid: 1 person, 50.00%
  4. Mycamine: 1 person, 50.00%
  5. Fosamax Plus D: 1 person, 50.00%
  6. Fosamax: 1 person, 50.00%
  7. Alendronate Sodium: 1 person, 50.00%

Other side effects people have besides Dupuytren's contracture *:

  1. Femur Fracture: 2 people, 100.00%
  2. Fall: 2 people, 100.00%
  3. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 2 people, 100.00%
  4. Osteoporosis (bones weak and more likely to break): 2 people, 100.00%
  5. Uterine Cyst: 1 person, 50.00%
  6. Intervertebral Disc Disorder (spinal disc disorder): 1 person, 50.00%
  7. Hypersensitivity: 1 person, 50.00%
  8. Hyperkeratosis (thickening of the outer layer of the skin): 1 person, 50.00%
  9. Gait Disturbance: 1 person, 50.00%
  10. Foot Fracture: 1 person, 50.00%

* Approximation only. Some reports may have incomplete information.

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Drugs with ingredients of cyanocobalamin, their effectiveness, alternatives and more:

How the study uses the data?

The study uses data from the FDA. It is based on cyanocobalamin. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


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DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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