Gastrointestinal inflammation and drugs of ingredients of cyclophosphamide - a phase IV clinical study of FDA data
Gastrointestinal inflammation is found among people who take drugs with ingredients of cyclophosphamide, especially for people who are female, 60+ old , have been taking the drugs for < 1 month. This phase IV clinical study is created by eHealthMe based on reports of 155,197 people who have side effects when taking drugs with ingredients of cyclophosphamide from the FDA, and is updated regularly.
Drug(s) considered in the study (i.e. both brand name and generic drugs): Cyclophosphamide, Cytoxan, Lyophilized cytoxan, Neosar.
With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.
155,197 people reported to have side effects when taking drugs with ingredients of cyclophosphamide.
Among them, 141 people (0.09%) have Gastrointestinal inflammation
What is Gastrointestinal inflammation?
Gastrointestinal inflammation (inflammation of stomach and intestine) is found to be associated with 755 drugs and 490 conditions by eHealthMe.
Number of reports submitted per year:
Time on drugs with ingredients of cyclophosphamide when people have Gastrointestinal inflammation *:
- < 1 month: 54.55 %
- 1 - 6 months: 36.36 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 4.55 %
- 2 - 5 years: 4.55 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
Gender of people who have Gastrointestinal inflammation when taking drugs with ingredients of cyclophosphamide *:
- female: 51.85 %
- male: 48.15 %
Age of people who have Gastrointestinal inflammation when taking drugs with ingredients of cyclophosphamide *:
- 0-1: 0.0 %
- 2-9: 8.45 %
- 10-19: 2.8200000000000003 %
- 20-29: 12.68 %
- 30-39: 2.8200000000000003 %
- 40-49: 25.35 %
- 50-59: 14.08 %
- 60+: 33.8 %
Conditions people have *:
- Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 18 people, 12.77%
- Burkitt Lymphoma (cancer of the lymphatic system): 12 people, 8.51%
- Bone Marrow Conditioning Regimen: 8 people, 5.67%
- Tachyarrhythmia (disturbance of the heart rhythm in which the heart rate is abnormally increased): 7 people, 4.96%
- High Blood Pressure: 7 people, 4.96%
- Hyperlipidaemia (presence of excess lipids in the blood): 7 people, 4.96%
- Hyperthyroidism (over activity of the thyroid gland): 7 people, 4.96%
- Chromosome Analysis Abnormal: 6 people, 4.26%
- Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 6 people, 4.26%
- Metastases To Skin (cancer spreads to skin): 4 people, 2.84%
Other drugs people take *:
- Etoposide: 57 people, 40.43%
- Dexamethasone: 56 people, 39.72%
- Cisplatin: 52 people, 36.88%
- Bortezomib: 51 people, 36.17%
- Melphalan: 49 people, 34.75%
- Methotrexate: 13 people, 9.22%
- Prednisone: 8 people, 5.67%
- Cytarabine: 6 people, 4.26%
- Sprycel: 6 people, 4.26%
- Carfilzomib: 5 people, 3.55%
Other side effects people have besides Gastrointestinal inflammation *:
- Stomatitis (inflammation of mucous membrane of mouth): 22 people, 15.60%
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 21 people, 14.89%
- Diarrhea: 19 people, 13.48%
- Febrile Neutropenia (fever with reduced white blood cells): 17 people, 12.06%
- Nausea And Vomiting: 14 people, 9.93%
- Thrombocytopenia (decrease of platelets in blood): 14 people, 9.93%
- Nausea (feeling of having an urge to vomit): 11 people, 7.80%
- Abdominal Pain: 10 people, 7.09%
- Anaemia (lack of blood): 10 people, 7.09%
- Fever: 10 people, 7.09%
* Approximation only. Some reports may have incomplete information.
How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Schwerd T, Pandey S, Yang HT, Bagola K, Jameson E, Jung J, Lachmann RH, Shah N, Patel SY, Booth C, Runz H, "Impaired antibacterial autophagy links granulomatous intestinal inflammation in Niemann–Pick disease type C1 and XIAP deficiency with NOD2 variants in Crohn9s disease", Gut, 2016 Mar .
- Hu P, Lu L, Hu B, Deng F, Fei WJ, "Cyclophosphamide‐Induced Hypertensive Encephalopathy in a Young Girl With Lupus", The Journal of Clinical Hypertension, 2012 Apr .
Drugs with ingredients of cyclophosphamide, their effectiveness, alternatives and more:
How the study uses the data?
The study uses data from the FDA. It is based on cyclophosphamide. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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