Dupuytren's contracture and drugs of ingredients of dalfampridine - a phase IV clinical study of FDA data


Summary:

Dupuytren's contracture is reported only by a few people who take drugs with ingredients of dalfampridine. This phase IV clinical study analyzes 79,156 people who have side effects while taking drugs with ingredients of dalfampridine from the the FDA. Among them, 2 have Dupuytren's contracture. Find out below who they are, when they have Dupuytren's contracture and more.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Ampyra, Dalfampridine.

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On Aug, 09, 2022

79,156 people reported to have side effects when taking drugs with ingredients of dalfampridine.
Among them, 2 people (0.0%) have Dupuytren's contracture


What is Dupuytren's contracture?

Dupuytren's contracture (thickening of the fibrous tissue layer underneath the skin of the palm and fingers) is found to be associated with 443 drugs and 204 conditions by eHealthMe.

Number of reports submitted per year:

Could drugs with ingredients of dalfampridine cause Dupuytren's contracture?

Time on drugs with ingredients of dalfampridine when people have Dupuytren's contracture *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 100 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Dupuytren's contracture when taking drugs with ingredients of dalfampridine *:

  • female: 0.0 %
  • male: 100 %

Age of people who have Dupuytren's contracture when taking drugs with ingredients of dalfampridine *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

Conditions people have *:

  1. Pain: 2 people, 100.00%
  2. Gait Disturbance: 2 people, 100.00%
  3. Dysaesthesia (abnormal sensation): 1 person, 50.00%
  4. Bladder Disorder: 1 person, 50.00%

Other drugs people take *:

  1. Vitamin E: 2 people, 100.00%
  2. Vitamin D3: 2 people, 100.00%
  3. Vitamin C: 2 people, 100.00%
  4. Tysabri: 2 people, 100.00%
  5. Lamisil: 2 people, 100.00%
  6. Fish Oil: 2 people, 100.00%
  7. Centrum Silver: 2 people, 100.00%
  8. Oxybutynin: 1 person, 50.00%
  9. Lasix: 1 person, 50.00%
  10. Avonex: 1 person, 50.00%

Other side effects people have besides Dupuytren's contracture *:

  1. Joint Swelling: 2 people, 100.00%
  2. Confusion: 2 people, 100.00%
  3. Nerve Root Compression: 2 people, 100.00%
  4. Neurogenic Bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion): 2 people, 100.00%
  5. Pain: 2 people, 100.00%
  6. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 2 people, 100.00%
  7. Fear Of Falling: 2 people, 100.00%
  8. Insomnia (sleeplessness): 2 people, 100.00%
  9. Defaecation Urgency (a sudden compelling urge to defecate): 2 people, 100.00%
  10. Cognitive Disorder (mental health disorders affects learning, memory, perception, and problem solving): 2 people, 100.00%

* Approximation only. Some reports may have incomplete information.


How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Drugs with ingredients of dalfampridine, their effectiveness, alternatives and more:

How the study uses the data?

The study uses data from the FDA. It is based on dalfampridine. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

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