Peripheral swelling and drugs of ingredients of dapsone - a phase IV clinical study of FDA data


Summary:

Peripheral swelling is found among people who take drugs with ingredients of dapsone, especially for people who are female, 60+ old , have been taking the drugs for < 1 month. This phase IV clinical study is created by eHealthMe based on reports of 10,817 people who have side effects when taking drugs with ingredients of dapsone from the FDA, and is updated regularly.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Aczone, Dapsone.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.


On Dec, 05, 2022

10,817 people reported to have side effects when taking drugs with ingredients of dapsone.
Among them, 82 people (0.76%) have Peripheral swelling


What is Peripheral swelling?

Peripheral swelling is found to be associated with 2,104 drugs and 1,574 conditions by eHealthMe.

Number of reports submitted per year:

Could drugs with ingredients of dapsone cause Peripheral swelling?

Time on drugs with ingredients of dapsone when people have Peripheral swelling *:

  • < 1 month: 33.33 %
  • 1 - 6 months: 33.33 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 33.33 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Peripheral swelling when taking drugs with ingredients of dapsone *:

  • female: 54.29 %
  • male: 45.71 %

Age of people who have Peripheral swelling when taking drugs with ingredients of dapsone *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 7.14 %
  • 30-39: 7.14 %
  • 40-49: 9.52 %
  • 50-59: 11.9 %
  • 60+: 64.29 %

Conditions people have *:

  1. Multiple Myeloma (cancer of the plasma cells): 11 people, 13.41%
  2. Hiv Infection: 6 people, 7.32%
  3. Neuropathy Peripheral (surface nerve damage): 6 people, 7.32%
  4. Burkitt Lymphoma (cancer of the lymphatic system): 6 people, 7.32%
  5. Encephalitis Viral (inflammation of the brain due to viral infection): 5 people, 6.10%
  6. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 6.10%
  7. Constipation: 5 people, 6.10%
  8. Sleep Disorder: 4 people, 4.88%
  9. Restless Leg Syndrome (a powerful urge to move your legs): 4 people, 4.88%
  10. Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 4 people, 4.88%

Other drugs people take *:

  1. Vitamin D3: 12 people, 14.63%
  2. Amlodipine: 11 people, 13.41%
  3. Revlimid: 10 people, 12.20%
  4. Vitamin B12: 9 people, 10.98%
  5. Lasix: 8 people, 9.76%
  6. Lyrica: 8 people, 9.76%
  7. Probiotic: 6 people, 7.32%
  8. Vitamin C: 6 people, 7.32%
  9. Linzess: 6 people, 7.32%
  10. Oxycodone: 5 people, 6.10%

Other side effects people have besides Peripheral swelling *:

  1. Rashes (redness): 26 people, 31.71%
  2. Breathing Difficulty: 20 people, 24.39%
  3. Nausea (feeling of having an urge to vomit): 18 people, 21.95%
  4. Fatigue (feeling of tiredness): 18 people, 21.95%
  5. Weakness: 17 people, 20.73%
  6. Pain In Extremity: 15 people, 18.29%
  7. Itching: 14 people, 17.07%
  8. Pain: 14 people, 17.07%
  9. Weight Increased: 12 people, 14.63%
  10. Constipation: 12 people, 14.63%

* Approximation only. Some reports may have incomplete information.


How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

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Drugs with ingredients of dapsone, their effectiveness, alternatives and more:

How the study uses the data?

The study uses data from the FDA. It is based on dapsone. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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