Mycosis fungoides and drugs of ingredients of ketoconazole - a phase IV clinical study of FDA data


Mycosis fungoides is found among people who take drugs with ingredients of ketoconazole, especially for people who are male, 40-49 old , have been taking the drugs for < 1 month. This phase IV clinical study is created by eHealthMe based on reports of 18,208 people who have side effects when taking drugs with ingredients of ketoconazole from the FDA, and is updated regularly.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Extina, Ketoconazole, Ketozole, Nizoral, Nizoral a-d, Nizoral anti-dandruff, Xolegel.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Feb, 07, 2023

18,208 people reported to have side effects when taking drugs with ingredients of ketoconazole.
Among them, 11 people (0.06%) have Mycosis fungoides

What is Mycosis fungoides?

Mycosis fungoides (lymphocytes (a type of white blood cell) become malignant (cancerous) and affect the skin) is found to be associated with 446 drugs and 231 conditions by eHealthMe.

Number of reports submitted per year:

Could drugs with ingredients of ketoconazole cause Mycosis fungoides?

Time on drugs with ingredients of ketoconazole when people have Mycosis fungoides *:

  • < 1 month: 50 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 50 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Mycosis fungoides when taking drugs with ingredients of ketoconazole *:

  • female: 9.09 %
  • male: 90.91 %

Age of people who have Mycosis fungoides when taking drugs with ingredients of ketoconazole *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 81.82 %
  • 50-59: 9.09 %
  • 60+: 9.09 %

Conditions people have *:

  1. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 8 people, 72.73%
  2. High Blood Pressure: 1 person, 9.09%
  3. Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 1 person, 9.09%
  4. Body Tinea (ringworm of the body): 1 person, 9.09%

Other drugs people take *:

  1. Flexeril: 8 people, 72.73%
  2. Allegra D 24 Hour: 8 people, 72.73%
  3. Triamcinolone: 8 people, 72.73%
  4. Temovate: 8 people, 72.73%
  5. Targretin: 8 people, 72.73%
  6. Simvastatin: 8 people, 72.73%
  7. Amoxicillin: 8 people, 72.73%
  8. Elidel: 8 people, 72.73%
  9. Fluocinonide: 8 people, 72.73%
  10. Oxsoralen-Ultra: 8 people, 72.73%

Other side effects people have besides Mycosis fungoides *:

  1. General Physical Health Deterioration (weak health status): 8 people, 72.73%
  2. Actinic Keratosis (skin disease due to sun exposure): 8 people, 72.73%
  3. Rashes (redness): 8 people, 72.73%
  4. Pyoderma (any skin disease that is pyogenic): 8 people, 72.73%
  5. Peripheral T-Cell Lymphoma Unspecified (peripheral t-cell cancer unspecified): 8 people, 72.73%
  6. Oedema Peripheral (superficial swelling): 8 people, 72.73%
  7. Sunburn: 7 people, 63.64%
  8. Weakness: 4 people, 36.36%
  9. Acute Respiratory Failure: 4 people, 36.36%
  10. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 4 people, 36.36%

* Approximation only. Some reports may have incomplete information.

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Drugs with ingredients of ketoconazole, their effectiveness, alternatives and more:

How the study uses the data?

The study uses data from the FDA. It is based on ketoconazole. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


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DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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