Basedow's disease and drugs of ingredients of medroxyprogesterone acetate - a phase IV clinical study of FDA data
Basedow's disease is found among people who take drugs with ingredients of medroxyprogesterone acetate, especially for people who are female, 40-49 old , have been taking the drugs for < 1 month. This phase IV clinical study is created by eHealthMe based on reports of 63,786 people who have side effects when taking drugs with ingredients of medroxyprogesterone acetate from the FDA, and is updated regularly.
Drug(s) considered in the study (i.e. both brand name and generic drugs): Amen, Curretab, Cycrin, Depo-provera, Depo-subq provera 104, Medroxyprogesterone acetate, Provera.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
63,786 people reported to have side effects when taking drugs with ingredients of medroxyprogesterone acetate.
Among them, 14 people (0.02%) have Basedow's disease
What is Basedow's disease?
Basedow's disease (autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones) is found to be associated with 735 drugs and 382 conditions by eHealthMe.
Number of reports submitted per year:
Time on drugs with ingredients of medroxyprogesterone acetate when people have Basedow's disease *:
- < 1 month: 33.33 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 33.33 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 33.33 %
- 10+ years: 0.0 %
Gender of people who have Basedow's disease when taking drugs with ingredients of medroxyprogesterone acetate *:
- female: 100 %
- male: 0.0 %
Age of people who have Basedow's disease when taking drugs with ingredients of medroxyprogesterone acetate *:
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 8.33 %
- 30-39: 33.33 %
- 40-49: 33.33 %
- 50-59: 16.67 %
- 60+: 8.33 %
Conditions people have *:
- Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 4 people, 28.57%
- Menopause (end of monthly cycles in women): 3 people, 21.43%
- Menopausal Symptoms: 3 people, 21.43%
- Hot Flush (sudden feelings of heat): 2 people, 14.29%
- High Blood Cholesterol: 2 people, 14.29%
- Glaucoma (increased fluid pressure in the eye with vision loss): 2 people, 14.29%
- Endometrial Cancer: 2 people, 14.29%
- Diabetes: 2 people, 14.29%
- Depression: 2 people, 14.29%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 14.29%
Other drugs people take *:
- Gravol: 4 people, 28.57%
- Benadryl: 4 people, 28.57%
- Prempro: 4 people, 28.57%
- Glucophage: 3 people, 21.43%
- Norvasc: 3 people, 21.43%
- Restoril: 3 people, 21.43%
- Lipitor: 3 people, 21.43%
- Progesterone: 3 people, 21.43%
- Tylenol: 3 people, 21.43%
- Vioxx: 3 people, 21.43%
Other side effects people have besides Basedow's disease *:
- Arrhythmias (irregular heartbeat): 7 people, 50.00%
- Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 7 people, 50.00%
- Weakness: 6 people, 42.86%
- Blood Thyroid Stimulating Hormone Decreased: 6 people, 42.86%
- Weight Increased: 6 people, 42.86%
- Breathing Difficulty: 6 people, 42.86%
- Chest Pain: 6 people, 42.86%
- Hyperhidrosis (abnormally increased sweating): 5 people, 35.71%
- High Blood Cholesterol: 5 people, 35.71%
- Tremor (trembling or shaking movements in one or more parts of your body): 5 people, 35.71%
* Approximation only. Some reports may have incomplete information.
How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Bahall M, Reyes AJ, Ramcharan K, Hosein N, Seegobin K, Bahall K, Sharma H, Dhansingh S, Mahabir A, "Neuro-ophthalmological manifestations after intramuscular medroxyprogesterone: a forme fruste of idiopathic intracranial hypertension?", Neurology international, 2016 Sep .
Drugs with ingredients of medroxyprogesterone acetate, their effectiveness, alternatives and more:
How the study uses the data?
The study uses data from the FDA. It is based on medroxyprogesterone acetate. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Guaifenesin and Diamox drug interaction - 17 seconds ago
- Kesimpta and Nausea And Vomiting - 17 seconds ago
- Estraderm and Glimepiride drug interaction - 18 seconds ago
- Prilosec and Bilirubin Conjugated Increased - 27 seconds ago
- Cymbalta and Bladder Disorder - 37 seconds ago
- Votrient and Neurofibrosarcoma - 55 seconds ago
- Norvasc and Ingrowing Nail - 56 seconds ago
- Cialis and Nausea And Vomiting - a minute ago
- Zomig and Eplerenone drug interaction - a minute ago
- Delatestryl and Ddavp drug interaction - a minute ago