Nosebleed and drugs of ingredients of memantine hydrochloride - a phase IV clinical study of FDA data


Summary:

Nosebleed is found among people who take drugs with ingredients of memantine hydrochloride, especially for people who are female, 60+ old , have been taking the drugs for < 1 month. This phase IV clinical study is created by eHealthMe based on reports of 18,388 people who have side effects when taking drugs with ingredients of memantine hydrochloride from the FDA, and is updated regularly.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Memantine hydrochloride, Namenda, Namenda xr.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.


On Nov, 24, 2022

18,388 people reported to have side effects when taking drugs with ingredients of memantine hydrochloride.
Among them, 62 people (0.34%) have Nosebleed


What is Nosebleed?

Nosebleed (bleeding from nose) is found to be associated with 3,223 drugs and 2,828 conditions by eHealthMe.

Number of reports submitted per year:

Could drugs with ingredients of memantine hydrochloride cause Nosebleed?

Time on drugs with ingredients of memantine hydrochloride when people have Nosebleed *:

  • < 1 month: 75.0 %
  • 1 - 6 months: 12.5 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 12.5 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Nosebleed when taking drugs with ingredients of memantine hydrochloride *:

  • female: 53.23 %
  • male: 46.77 %

Age of people who have Nosebleed when taking drugs with ingredients of memantine hydrochloride *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 1.75 %
  • 40-49: 1.75 %
  • 50-59: 3.51 %
  • 60+: 92.98 %

Conditions people have *:

  1. Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 17 people, 27.42%
  2. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 9 people, 14.52%
  3. Osteoporosis (bones weak and more likely to break): 6 people, 9.68%
  4. Pulmonary Embolism (blockage of the main artery of the lung): 5 people, 8.06%
  5. Prostate Cancer: 4 people, 6.45%
  6. Waldenstrom's Macroglobulinaemia (cancer affects small lymphocytes (white blood cells)): 4 people, 6.45%
  7. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 4 people, 6.45%
  8. Diabetes: 3 people, 4.84%
  9. High Blood Pressure: 3 people, 4.84%
  10. Renal Cell Carcinoma (a kidney cancer): 2 people, 3.23%

Other drugs people take *:

  1. Aricept: 18 people, 29.03%
  2. Aspirin: 11 people, 17.74%
  3. Coumadin: 10 people, 16.13%
  4. Xarelto: 8 people, 12.90%
  5. Digoxin: 7 people, 11.29%
  6. Exelon: 6 people, 9.68%
  7. Norvasc: 5 people, 8.06%
  8. Vitamin D: 5 people, 8.06%
  9. Lasix: 5 people, 8.06%
  10. Omeprazole: 5 people, 8.06%

Other side effects people have besides Nosebleed *:

  1. Fall: 13 people, 20.97%
  2. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 9 people, 14.52%
  3. Head Injury: 7 people, 11.29%
  4. Fatigue (feeling of tiredness): 7 people, 11.29%
  5. Fever: 7 people, 11.29%
  6. Tremor (trembling or shaking movements in one or more parts of your body): 7 people, 11.29%
  7. Confusional State: 7 people, 11.29%
  8. High Blood Pressure: 6 people, 9.68%
  9. Breathing Difficulty: 6 people, 9.68%
  10. Eye Haemorrhage (bleeding in the eye): 6 people, 9.68%

* Approximation only. Some reports may have incomplete information.


How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Drugs with ingredients of memantine hydrochloride, their effectiveness, alternatives and more:

How the study uses the data?

The study uses data from the FDA. It is based on memantine hydrochloride. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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