Nausea and vomiting and drugs of ingredients of methylphenidate hydrochloride - a phase IV clinical study of FDA data


Summary:

Nausea and vomiting is found among people who take drugs with ingredients of methylphenidate hydrochloride, especially for people who are female, 10-19 old , have been taking the drugs for < 1 month. This phase IV clinical study is created by eHealthMe based on reports of 57,688 people who have side effects when taking drugs with ingredients of methylphenidate hydrochloride from the FDA, and is updated regularly.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Adhansia xr, Aptensio xr, Concerta, Jornay pm, Metadate cd, Metadate er, Methylin, Methylin er, Methylphenidate hydrochloride, Quillichew er, Quillivant xr, Relexxii, Ritalin, Ritalin la, Ritalin-sr.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.


On Sep, 26, 2022

57,688 people reported to have side effects when taking drugs with ingredients of methylphenidate hydrochloride.
Among them, 1,912 people (3.31%) have Nausea and vomiting


What is Nausea and vomiting?

Nausea and vomiting is found to be associated with 4,550 drugs and 5,396 conditions by eHealthMe.

Number of reports submitted per year:

Could drugs with ingredients of methylphenidate hydrochloride cause Nausea and vomiting?

Time on drugs with ingredients of methylphenidate hydrochloride when people have Nausea and vomiting *:

  • < 1 month: 46.3 %
  • 1 - 6 months: 20.37 %
  • 6 - 12 months: 6.79 %
  • 1 - 2 years: 9.88 %
  • 2 - 5 years: 11.73 %
  • 5 - 10 years: 3.7 %
  • 10+ years: 1.23 %

Gender of people who have Nausea and vomiting when taking drugs with ingredients of methylphenidate hydrochloride *:

  • female: 57.14 %
  • male: 42.86 %

Age of people who have Nausea and vomiting when taking drugs with ingredients of methylphenidate hydrochloride *:

  • 0-1: 0.27 %
  • 2-9: 13.25 %
  • 10-19: 25.88 %
  • 20-29: 12.35 %
  • 30-39: 10.57 %
  • 40-49: 14.21 %
  • 50-59: 10.84 %
  • 60+: 12.63 %

Conditions people have *:

  1. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 237 people, 12.40%
  2. Pain: 131 people, 6.85%
  3. Stress And Anxiety: 89 people, 4.65%
  4. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 89 people, 4.65%
  5. High Blood Pressure: 59 people, 3.09%
  6. Nausea (feeling of having an urge to vomit): 46 people, 2.41%
  7. Migraine (headache): 45 people, 2.35%
  8. Metastases To Bone (cancer spreads to bone): 43 people, 2.25%
  9. Drowsiness: 42 people, 2.20%
  10. Bipolar Disorder (mood disorder): 40 people, 2.09%

Other drugs people take *:

  1. Xyrem: 356 people, 18.62%
  2. Zofran: 120 people, 6.28%
  3. Prozac: 118 people, 6.17%
  4. Prilosec: 116 people, 6.07%
  5. Neurontin: 115 people, 6.01%
  6. Ambien: 100 people, 5.23%
  7. Abilify: 100 people, 5.23%
  8. Ativan: 96 people, 5.02%
  9. Adderall: 96 people, 5.02%
  10. Oxycontin: 96 people, 5.02%

Other side effects people have besides Nausea and vomiting *:

  1. Nausea (feeling of having an urge to vomit): 934 people, 48.85%
  2. Headache (pain in head): 450 people, 23.54%
  3. Diarrhea: 364 people, 19.04%
  4. Fatigue (feeling of tiredness): 355 people, 18.57%
  5. Dizziness: 353 people, 18.46%
  6. Stress And Anxiety: 286 people, 14.96%
  7. Pain: 266 people, 13.91%
  8. Weight Decreased: 239 people, 12.50%
  9. Weakness: 231 people, 12.08%
  10. High Blood Pressure: 212 people, 11.09%

* Approximation only. Some reports may have incomplete information.


How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

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Drugs with ingredients of methylphenidate hydrochloride, their effectiveness, alternatives and more:

How the study uses the data?

The study uses data from the FDA. It is based on methylphenidate hydrochloride. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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