Ototoxicity and drugs of ingredients of minocycline hydrochloride - a phase IV clinical study of FDA data
Ototoxicity is found among people who take drugs with ingredients of minocycline hydrochloride, especially for people who are male, 30-39 old , have been taking the drugs for < 1 month. This phase IV clinical study is created by eHealthMe based on reports of 21,372 people who have side effects when taking drugs with ingredients of minocycline hydrochloride from the FDA, and is updated regularly.
Drug(s) considered in the study (i.e. both brand name and generic drugs): Amzeeq, Arestin, Dynacin, Minocin, Minocycline hydrochloride, Minolira, Ximino, Zilxi.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
21,372 people reported to have side effects when taking drugs with ingredients of minocycline hydrochloride.
Among them, 19 people (0.09%) have Ototoxicity
What is Ototoxicity?
Ototoxicity (damage to the ear) is found to be associated with 598 drugs and 336 conditions by eHealthMe.
Number of reports submitted per year:
Time on drugs with ingredients of minocycline hydrochloride when people have Ototoxicity *:
- < 1 month: 100 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
Gender of people who have Ototoxicity when taking drugs with ingredients of minocycline hydrochloride *:
- female: 11.11 %
- male: 88.89 %
Age of people who have Ototoxicity when taking drugs with ingredients of minocycline hydrochloride *:
- 0-1: 0.0 %
- 2-9: 12.5 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 56.25 %
- 40-49: 25.0 %
- 50-59: 0.0 %
- 60+: 6.25 %
Conditions people have *:
- Mycobacterium Abscessus Infection (rapid growing bacterial infection): 16 people, 84.21%
- Pneumonia: 3 people, 15.79%
- Lung Disorder (lung disease): 2 people, 10.53%
- Cystic Fibrosis (disease of the secretary glands): 2 people, 10.53%
- Osteomyelitis (infection of bone): 1 person, 5.26%
- Blood Disorder: 1 person, 5.26%
- Bacteraemia (presence of bacteria in the blood): 1 person, 5.26%
- Atypical Mycobacterial Infection (infections caused by several types of mycobacterium similar to the germ that causes tuberculosis): 1 person, 5.26%
Other drugs people take *:
- Imipenem And Cilastatin: 2 people, 10.53%
- Cefoxitin: 2 people, 10.53%
- Azithromycin: 2 people, 10.53%
- Tigecycline: 1 person, 5.26%
- Prednisolone: 1 person, 5.26%
- Moxifloxacin: 1 person, 5.26%
- Meropenem: 1 person, 5.26%
- Linezolid: 1 person, 5.26%
- Lamprene: 1 person, 5.26%
- Clarithromycin: 1 person, 5.26%
Other side effects people have besides Ototoxicity *:
- Facial Paralysis (loss of function of face muscle): 11 people, 57.89%
- Acoustic Neuroma (primary intracranial tumour): 10 people, 52.63%
- Insomnia (sleeplessness): 10 people, 52.63%
- Deafness Neurosensory: 8 people, 42.11%
- Fatigue (feeling of tiredness): 8 people, 42.11%
- Balance Disorder: 7 people, 36.84%
- Nausea (feeling of having an urge to vomit): 7 people, 36.84%
- Deafness Unilateral: 6 people, 31.58%
- Vestibular Disorder (disorders of the body's balance (vestibular) system in the inner ear): 5 people, 26.32%
- Neurilemmoma Benign (a non cancer tumour that typically grows on the myelin sheath of nerves in the head or neck): 3 people, 15.79%
* Approximation only. Some reports may have incomplete information.
How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Drugs with ingredients of minocycline hydrochloride, their effectiveness, alternatives and more:
How the study uses the data?
The study uses data from the FDA. It is based on minocycline hydrochloride. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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