Nasal congestion and drugs of ingredients of oxybutynin chloride - a phase IV clinical study of FDA data


Summary:

Nasal congestion is found among people who take drugs with ingredients of oxybutynin chloride, especially for people who are female, 60+ old , have been taking the drugs for < 1 month. This phase IV clinical study is created by eHealthMe based on reports of 24,208 people who have side effects when taking drugs with ingredients of oxybutynin chloride from the FDA, and is updated regularly.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Ditropan, Ditropan xl, Gelnique, Oxybutyin chloride, Oxybutynin chloride.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.


On Dec, 03, 2022

24,208 people reported to have side effects when taking drugs with ingredients of oxybutynin chloride.
Among them, 77 people (0.32%) have Nasal congestion


What is Nasal congestion?

Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels) is found to be associated with 2,996 drugs and 2,202 conditions by eHealthMe.

Number of reports submitted per year:

Could drugs with ingredients of oxybutynin chloride cause Nasal congestion?

Time on drugs with ingredients of oxybutynin chloride when people have Nasal congestion *:

  • < 1 month: 40 %
  • 1 - 6 months: 20 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 40 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Nasal congestion when taking drugs with ingredients of oxybutynin chloride *:

  • female: 53.25 %
  • male: 46.75 %

Age of people who have Nasal congestion when taking drugs with ingredients of oxybutynin chloride *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 2.94 %
  • 30-39: 7.35 %
  • 40-49: 7.35 %
  • 50-59: 23.53 %
  • 60+: 58.82 %

Conditions people have *:

  1. High Blood Pressure: 10 people, 12.99%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 7.79%
  3. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 6 people, 7.79%
  4. High Blood Cholesterol: 6 people, 7.79%
  5. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 5 people, 6.49%
  6. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 6.49%
  7. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 5 people, 6.49%
  8. Depression: 4 people, 5.19%
  9. Ill-Defined Disorder: 4 people, 5.19%
  10. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 5.19%

Other drugs people take *:

  1. Aspirin: 19 people, 24.68%
  2. Prilosec: 18 people, 23.38%
  3. Celebrex: 16 people, 20.78%
  4. Atenolol: 15 people, 19.48%
  5. Nexium: 15 people, 19.48%
  6. Lasix: 15 people, 19.48%
  7. Omeprazole: 14 people, 18.18%
  8. Zyrtec: 13 people, 16.88%
  9. Zometa: 13 people, 16.88%
  10. Zofran: 11 people, 14.29%

Other side effects people have besides Nasal congestion *:

  1. Fatigue (feeling of tiredness): 29 people, 37.66%
  2. Urinary Tract Infection: 29 people, 37.66%
  3. Headache (pain in head): 27 people, 35.06%
  4. Cough: 25 people, 32.47%
  5. Joint Pain: 23 people, 29.87%
  6. Constipation: 22 people, 28.57%
  7. Hypoaesthesia (reduced sense of touch or sensation): 20 people, 25.97%
  8. Pain: 20 people, 25.97%
  9. Fall: 18 people, 23.38%
  10. Chest Pain: 18 people, 23.38%

* Approximation only. Some reports may have incomplete information.


How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Drugs with ingredients of oxybutynin chloride, their effectiveness, alternatives and more:

How the study uses the data?

The study uses data from the FDA. It is based on oxybutynin chloride. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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