Collapse of lung and drugs of ingredients of paclitaxel - a phase IV clinical study of FDA data


Summary:

Collapse of lung is found among people who take drugs with ingredients of paclitaxel, especially for people who are female, 60+ old , have been taking the drugs for < 1 month. This phase IV clinical study is created by eHealthMe based on reports of 115,171 people who have side effects when taking drugs with ingredients of paclitaxel from the FDA, and is updated regularly.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Abraxane, Pacitaxel, Paclitaxel, Taxol.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.


On Oct, 01, 2022

115,171 people reported to have side effects when taking drugs with ingredients of paclitaxel.
Among them, 25 people (0.02%) have Collapse of lung


What is Collapse of lung?

Collapse of lung (functional breakdown of lung) is found to be associated with 735 drugs and 362 conditions by eHealthMe.

Number of reports submitted per year:

Could drugs with ingredients of paclitaxel cause Collapse of lung?

Time on drugs with ingredients of paclitaxel when people have Collapse of lung *:

  • < 1 month: 66.67 %
  • 1 - 6 months: 33.33 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Collapse of lung when taking drugs with ingredients of paclitaxel *:

  • female: 68 %
  • male: 32 %

Age of people who have Collapse of lung when taking drugs with ingredients of paclitaxel *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 12.5 %
  • 50-59: 37.5 %
  • 60+: 50.0 %

Conditions people have *:

  1. Lung Neoplasm Malignant (cancer tumour of lung): 2 people, 8.00%
  2. Lung Cancer - Non-Small Cell (lung cancer): 2 people, 8.00%
  3. Non-Small Cell Lung Cancer Stage Iv: 1 person, 4.00%
  4. Non Small Cell Lung Cancer Stage Iv (the cancer has spread to other organs of the body): 1 person, 4.00%
  5. Nausea (feeling of having an urge to vomit): 1 person, 4.00%
  6. Metastases To Bone (cancer spreads to bone): 1 person, 4.00%
  7. Lung Cancer Stage Unspecified (Excl Metastatic Tumors To Lung): 1 person, 4.00%
  8. Crohn's Disease (condition that causes inflammation of the gastrointestinal tract): 1 person, 4.00%
  9. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 1 person, 4.00%

Other drugs people take *:

  1. Carboplatin: 8 people, 32.00%
  2. Gemcitabine: 6 people, 24.00%
  3. Zometa: 5 people, 20.00%
  4. Aredia: 5 people, 20.00%
  5. Percocet: 5 people, 20.00%
  6. Premarin: 4 people, 16.00%
  7. Anastrozole: 4 people, 16.00%
  8. Arimidex: 4 people, 16.00%
  9. Celexa: 4 people, 16.00%
  10. Ibuprofen: 4 people, 16.00%

Other side effects people have besides Collapse of lung *:

  1. Pleural Effusion (water on the lungs): 13 people, 52.00%
  2. Breathing Difficulty: 8 people, 32.00%
  3. Metastatic Neoplasm (spreadable cancer tumour): 7 people, 28.00%
  4. Pulmonary Embolism (blockage of the main artery of the lung): 6 people, 24.00%
  5. Haemoglobin Decreased: 6 people, 24.00%
  6. Pneumonia: 6 people, 24.00%
  7. Cough: 6 people, 24.00%
  8. Bone Disorder: 5 people, 20.00%
  9. Haematocrit Decreased: 5 people, 20.00%
  10. Atelectasis (partial or complete collapse of the lung): 5 people, 20.00%

* Approximation only. Some reports may have incomplete information.


How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Drugs with ingredients of paclitaxel, their effectiveness, alternatives and more:

How the study uses the data?

The study uses data from the FDA. It is based on paclitaxel. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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