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Umbilical hernia and drugs of ingredients of pantoprazole sodium - a phase IV clinical study of FDA data


Summary:

Umbilical hernia is found among people who take drugs with ingredients of pantoprazole sodium, especially for people who are male, 60+ old , have been taking the drugs for 2 - 5 years. This phase IV clinical study is created by eHealthMe based on reports of 335,032 people who have side effects when taking drugs with ingredients of pantoprazole sodium from the FDA, and is updated regularly.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Pantoprazole, Pantoprazole sodium, Protonix, Protonix iv.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Mar, 18, 2023

335,032 people reported to have side effects when taking drugs with ingredients of pantoprazole sodium.
Among them, 273 people (0.08%) have Umbilical hernia

What is Umbilical hernia?

Umbilical hernia (an outward bulging (protrusion) of the abdominal lining or part of the abdominal organ(s) through the area around the belly button) is found to be associated with 1,170 drugs and 627 conditions by eHealthMe.

Number of reports submitted per year:

Could drugs with ingredients of pantoprazole sodium cause Umbilical hernia?

Time on drugs with ingredients of pantoprazole sodium when people have Umbilical hernia *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 50 %
  • 2 - 5 years: 50 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Umbilical hernia when taking drugs with ingredients of pantoprazole sodium *:

  • female: 36.61 %
  • male: 63.39 %

Age of people who have Umbilical hernia when taking drugs with ingredients of pantoprazole sodium *:

  • 0-1: 0.47000000000000003 %
  • 2-9: 0.47000000000000003 %
  • 10-19: 0.9500000000000001 %
  • 20-29: 0.47000000000000003 %
  • 30-39: 1.9 %
  • 40-49: 9.48 %
  • 50-59: 32.7 %
  • 60+: 53.55 %

Conditions people have *:

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 65 people, 23.81%
  2. Pain: 49 people, 17.95%
  3. Asthma: 34 people, 12.45%
  4. High Blood Cholesterol: 33 people, 12.09%
  5. High Blood Pressure: 31 people, 11.36%
  6. Multiple Myeloma (cancer of the plasma cells): 28 people, 10.26%
  7. Joint Pain: 27 people, 9.89%
  8. Diarrhea: 26 people, 9.52%
  9. Fluid Retention (an abnormal accumulation of fluid in the blood): 25 people, 9.16%
  10. Seborrhoeic Dermatitis (a common, inflammatory skin condition that causes flaky, white to yellowish scales to form on oily areas such as the scalp): 24 people, 8.79%

Other drugs people take *:

  1. Lipitor: 95 people, 34.80%
  2. Lasix: 70 people, 25.64%
  3. Zometa: 67 people, 24.54%
  4. Folic Acid: 64 people, 23.44%
  5. Synthroid: 63 people, 23.08%
  6. Prednisone: 61 people, 22.34%
  7. Tylenol: 59 people, 21.61%
  8. Lomotil: 56 people, 20.51%
  9. Revlimid: 51 people, 18.68%
  10. Aspirin: 51 people, 18.68%

Other side effects people have besides Umbilical hernia *:

  1. Breathing Difficulty: 130 people, 47.62%
  2. Stress And Anxiety: 120 people, 43.96%
  3. Chest Pain: 90 people, 32.97%
  4. Joint Pain: 88 people, 32.23%
  5. Nausea (feeling of having an urge to vomit): 81 people, 29.67%
  6. Diarrhea: 79 people, 28.94%
  7. Fall: 78 people, 28.57%
  8. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 76 people, 27.84%
  9. Oedema Peripheral (superficial swelling): 71 people, 26.01%
  10. Dizziness: 71 people, 26.01%

* Approximation only. Some reports may have incomplete information.

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Drugs with ingredients of pantoprazole sodium, their effectiveness, alternatives and more:

How the study uses the data?

The study uses data from the FDA. It is based on pantoprazole sodium. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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