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Weight loss and drugs of ingredients of pioglitazone hydrochloride - a phase IV clinical study of FDA data


Summary:

Weight loss is found among people who take drugs with ingredients of pioglitazone hydrochloride, especially for people who are female, 60+ old , have been taking the drugs for 2 - 5 years. This phase IV clinical study is created by eHealthMe based on reports of 58,567 people who have side effects when taking drugs with ingredients of pioglitazone hydrochloride from the FDA, and is updated regularly.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Actos, Pioglitazone, Pioglitazone hydrochloride.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Feb, 07, 2023

58,567 people reported to have side effects when taking drugs with ingredients of pioglitazone hydrochloride.
Among them, 273 people (0.47%) have Weight loss

What is Weight loss?

Weight loss is found to be associated with 2,721 drugs and 2,196 conditions by eHealthMe.

Number of reports submitted per year:

Could drugs with ingredients of pioglitazone hydrochloride cause Weight loss?

Time on drugs with ingredients of pioglitazone hydrochloride when people have Weight loss *:

  • < 1 month: 11.54 %
  • 1 - 6 months: 15.38 %
  • 6 - 12 months: 11.54 %
  • 1 - 2 years: 11.54 %
  • 2 - 5 years: 34.62 %
  • 5 - 10 years: 3.85 %
  • 10+ years: 11.54 %

Gender of people who have Weight loss when taking drugs with ingredients of pioglitazone hydrochloride *:

  • female: 63.06 %
  • male: 36.94 %

Age of people who have Weight loss when taking drugs with ingredients of pioglitazone hydrochloride *:

  • 0-1: 0.49 %
  • 2-9: 0.0 %
  • 10-19: 0.49 %
  • 20-29: 1.94 %
  • 30-39: 15.53 %
  • 40-49: 26.21 %
  • 50-59: 26.21 %
  • 60+: 29.13 %

Conditions people have *:

  1. Depression: 42 people, 15.38%
  2. Bipolar Disorder (mood disorder): 36 people, 13.19%
  3. Sleep Disorder: 25 people, 9.16%
  4. High Blood Cholesterol: 25 people, 9.16%
  5. Multiple Myeloma (cancer of the plasma cells): 24 people, 8.79%
  6. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 24 people, 8.79%
  7. Insomnia (sleeplessness): 21 people, 7.69%
  8. Stress And Anxiety: 19 people, 6.96%
  9. High Blood Pressure: 16 people, 5.86%
  10. Hyperlipidaemia (presence of excess lipids in the blood): 10 people, 3.66%

Other drugs people take *:

  1. Seroquel: 82 people, 30.04%
  2. Lexapro: 59 people, 21.61%
  3. Lipitor: 56 people, 20.51%
  4. Lantus: 55 people, 20.15%
  5. Lisinopril: 52 people, 19.05%
  6. Aspirin: 50 people, 18.32%
  7. Nexium: 47 people, 17.22%
  8. Albuterol: 44 people, 16.12%
  9. Zyprexa: 44 people, 16.12%
  10. Abilify: 44 people, 16.12%

Other side effects people have besides Weight loss *:

  1. High Blood Cholesterol: 85 people, 31.14%
  2. Chest Pain: 81 people, 29.67%
  3. High Blood Pressure: 68 people, 24.91%
  4. Breathing Difficulty: 68 people, 24.91%
  5. Stress And Anxiety: 60 people, 21.98%
  6. Pain: 54 people, 19.78%
  7. Diabetes Mellitus Inadequate Control: 53 people, 19.41%
  8. Diarrhea: 51 people, 18.68%
  9. Abdominal Pain: 51 people, 18.68%
  10. Neuropathy Peripheral (surface nerve damage): 49 people, 17.95%

* Approximation only. Some reports may have incomplete information.

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Drugs with ingredients of pioglitazone hydrochloride, their effectiveness, alternatives and more:

How the study uses the data?

The study uses data from the FDA. It is based on pioglitazone hydrochloride. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

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DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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