Death and drugs of ingredients of simvastatin - a phase IV clinical study of FDA data
Death is found among people who take drugs with ingredients of simvastatin, especially for people who are male, 60+ old , have been taking the drugs for 2 - 5 years. This phase IV clinical study is created by eHealthMe based on reports of 310,515 people who have side effects when taking drugs with ingredients of simvastatin from the FDA, and is updated regularly.
Drug(s) considered in the study (i.e. both brand name and generic drugs): Flolipid, Simvastatin, Zocor.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
310,515 people reported to have side effects when taking drugs with ingredients of simvastatin.
Among them, 7,129 people (2.3%) died.
Number of reports submitted per year:
Time on drugs with ingredients of simvastatin when people died *:
- < 1 month: 15.17 %
- 1 - 6 months: 14.83 %
- 6 - 12 months: 8.97 %
- 1 - 2 years: 15.17 %
- 2 - 5 years: 21.38 %
- 5 - 10 years: 20.69 %
- 10+ years: 3.79 %
Gender of people who died when taking drugs with ingredients of simvastatin *:
- female: 40.26 %
- male: 59.74 %
Age of people who died when taking drugs with ingredients of simvastatin *:
- 0-1: 0.0 %
- 2-9: 0.02 %
- 10-19: 0.11 %
- 20-29: 0.30000000000000004 %
- 30-39: 1.65 %
- 40-49: 3.24 %
- 50-59: 10.38 %
- 60+: 84.31 %
Conditions people have *:
- Multiple Myeloma (cancer of the plasma cells): 451 people, 6.33%
- Diabetes: 304 people, 4.26%
- Pain: 290 people, 4.07%
- Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 256 people, 3.59%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 255 people, 3.58%
- Prostate Cancer: 203 people, 2.85%
- Parkinson's Disease: 199 people, 2.79%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 171 people, 2.40%
- Depression: 162 people, 2.27%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 158 people, 2.22%
Other drugs people take *:
- Lasix: 787 people, 11.04%
- Aspirin: 730 people, 10.24%
- Metformin: 634 people, 8.89%
- Plavix: 555 people, 7.79%
- Amlodipine: 541 people, 7.59%
- Lisinopril: 529 people, 7.42%
- Revlimid: 482 people, 6.76%
- Furosemide: 449 people, 6.30%
- Prilosec: 421 people, 5.91%
- Pantoprazole: 417 people, 5.85%
Other side effects people have when they died *:
- Acute Kidney Failure: 576 people, 8.08%
- Pain: 538 people, 7.55%
- Stress And Anxiety: 482 people, 6.76%
- Breathing Difficulty: 372 people, 5.22%
- Injury: 365 people, 5.12%
- Weakness: 348 people, 4.88%
- Fatigue (feeling of tiredness): 330 people, 4.63%
- Pneumonia: 316 people, 4.43%
- Fall: 305 people, 4.28%
- Renal Injury (kidney injury): 302 people, 4.24%
* Approximation only. Some reports may have incomplete information.
How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Drugs with ingredients of simvastatin, their effectiveness, alternatives and more:
How the study uses the data?
The study uses data from the FDA. It is based on simvastatin. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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