Hydropneumothorax and drugs of ingredients of st. john's wort - a phase IV clinical study of FDA data


Hydropneumothorax is found among people who take drugs with ingredients of st. john's wort, especially for people who are female, 50-59 old . This phase IV clinical study is created by eHealthMe based on reports of 1,353 people who have side effects when taking drugs with ingredients of st. john's wort from the FDA, and is updated regularly.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Amber, Amber touch-and-heal, Demon chaser, Fuga daemonum, Goatweed, Hardhay, Hypereikon, Hyperici herba, Hypericum perforatum, Klamath weed, Millepertuis, Rosin rose, Saynt johannes wort, Sjw, St. john's wort, Tipton weed.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Jan, 27, 2023

1,353 people reported to have side effects when taking drugs with ingredients of st. john's wort.
Among them, 12 people (0.89%) have Hydropneumothorax

What is Hydropneumothorax?

Hydropneumothorax (presence of both air and fluid in the pleural space (lungs)) is found to be associated with 314 drugs and 121 conditions by eHealthMe.

Number of reports submitted per year:

Could drugs with ingredients of st. john's wort cause Hydropneumothorax?

Gender of people who have Hydropneumothorax when taking drugs with ingredients of st. john's wort *:

  • female: 91.67 %
  • male: 8.33 %

Age of people who have Hydropneumothorax when taking drugs with ingredients of st. john's wort *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 100 %
  • 60+: 0.0 %

Conditions people have *:

  1. Bone Density Abnormal: 11 people, 91.67%
  2. Osteoporosis (bones weak and more likely to break): 4 people, 33.33%
  3. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 1 person, 8.33%

Other drugs people take *:

  1. Zovirax: 12 people, 100.00%
  2. Mucinex: 12 people, 100.00%
  3. Lexapro: 12 people, 100.00%
  4. Lasix: 12 people, 100.00%
  5. Klonopin: 12 people, 100.00%
  6. Fosamax: 12 people, 100.00%
  7. Flovent: 12 people, 100.00%
  8. Flonase: 12 people, 100.00%
  9. Effexor: 12 people, 100.00%
  10. Ditropan Xl: 12 people, 100.00%

Other side effects people have besides Hydropneumothorax *:

  1. Wound Infection Staphylococcal: 12 people, 100.00%
  2. Drowsiness: 12 people, 100.00%
  3. Injury Corneal: 12 people, 100.00%
  4. Injury: 12 people, 100.00%
  5. Idiopathic Pulmonary Fibrosis (chronic lung disease): 12 people, 100.00%
  6. Foot Deformity (functional disability of foot): 12 people, 100.00%
  7. Fibula Fracture: 12 people, 100.00%
  8. Fall: 12 people, 100.00%
  9. Faecal Incontinence (a lack of control over passing stool): 12 people, 100.00%
  10. Empyema (collection of pus in a cavity in the body): 12 people, 100.00%

* Approximation only. Some reports may have incomplete information.

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

How the study uses the data?

The study uses data from the FDA. It is based on st. john's wort. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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