Salivary gland enlargement and drugs of ingredients of thyrotropin alfa - a phase IV clinical study of FDA data


Summary:

Salivary gland enlargement is reported only by a few people who take drugs with ingredients of thyrotropin alfa. This phase IV clinical study analyzes 1,035 people who have side effects while taking drugs with ingredients of thyrotropin alfa from the the FDA. Among them, 4 have Salivary gland enlargement. Find out below who they are, when they have Salivary gland enlargement and more.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Thyrogen.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.


On Dec, 02, 2022

1,035 people reported to have side effects when taking drugs with ingredients of thyrotropin alfa.
Among them, 4 people (0.39%) have Salivary gland enlargement


What is Salivary gland enlargement?

Salivary gland enlargement (increased size of salivary gland) is found to be associated with 670 drugs and 316 conditions by eHealthMe.

Number of reports submitted per year:

Could drugs with ingredients of thyrotropin alfa cause Salivary gland enlargement?

Time on drugs with ingredients of thyrotropin alfa when people have Salivary gland enlargement *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Salivary gland enlargement when taking drugs with ingredients of thyrotropin alfa *:

  • female: 100 %
  • male: 0.0 %

Age of people who have Salivary gland enlargement when taking drugs with ingredients of thyrotropin alfa *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 25 %
  • 60+: 75 %

Other drugs people take *:

  1. Synthroid: 3 people, 75.00%
  2. Meclizine: 3 people, 75.00%
  3. Lyrica: 3 people, 75.00%
  4. Lisinopril: 3 people, 75.00%
  5. Lipitor: 3 people, 75.00%
  6. Januvia: 3 people, 75.00%
  7. Fortamet: 3 people, 75.00%
  8. Diovan: 3 people, 75.00%
  9. Demadex: 3 people, 75.00%
  10. Atenolol: 3 people, 75.00%

Other side effects people have besides Salivary gland enlargement *:

  1. Fall: 3 people, 75.00%
  2. Fainting (loss of consciousness and postural tone): 3 people, 75.00%
  3. Aptyalism (deficiency or absence of saliva): 3 people, 75.00%
  4. Dehydration (dryness resulting from the removal of water): 3 people, 75.00%
  5. Dry Mouth: 3 people, 75.00%
  6. Ecchymosis (a discoloration of the skin resulting from bleeding underneath): 3 people, 75.00%
  7. Acute Kidney Failure: 3 people, 75.00%
  8. Nosebleed (bleeding from nose): 3 people, 75.00%
  9. Iodine Uptake Increased: 2 people, 50.00%
  10. Gastroenteritis (inflammation of stomach and intestine): 2 people, 50.00%

* Approximation only. Some reports may have incomplete information.


How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Drugs with ingredients of thyrotropin alfa, their effectiveness, alternatives and more:

How the study uses the data?

The study uses data from the FDA. It is based on thyrotropin alfa. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

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