Procedural pain and drugs of ingredients of tocopherols and tocotrienols - a phase IV clinical study of FDA data


Summary:

Procedural pain is found among people who take drugs with ingredients of tocopherols and tocotrienols, especially for people who are female, 60+ old . This phase IV clinical study is created by eHealthMe based on reports of 37,202 people who have side effects when taking drugs with ingredients of tocopherols and tocotrienols from the FDA, and is updated regularly.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Vitamin e.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.


On May, 26, 2023

37,202 people reported to have side effects when taking drugs with ingredients of tocopherols and tocotrienols.
Among them, 85 people (0.23%) have Procedural pain


What is Procedural pain?

Procedural pain is found to be associated with 1,643 drugs and 859 conditions by eHealthMe.

Number of reports submitted per year:

Could drugs with ingredients of tocopherols and tocotrienols cause Procedural pain?

Gender of people who have Procedural pain when taking drugs with ingredients of tocopherols and tocotrienols *:

  • female: 66.67 %
  • male: 33.33 %

Age of people who have Procedural pain when taking drugs with ingredients of tocopherols and tocotrienols *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 1.67 %
  • 30-39: 6.67 %
  • 40-49: 5.0 %
  • 50-59: 21.67 %
  • 60+: 65.0 %

Conditions people have *:

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 21 people, 24.71%
  2. Psoriasis (immune-mediated disease that affects the skin): 21 people, 24.71%
  3. Crohn's Disease (condition that causes inflammation of the gastrointestinal tract): 17 people, 20.00%
  4. High Blood Pressure: 15 people, 17.65%
  5. Pain: 13 people, 15.29%
  6. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 11 people, 12.94%
  7. Depression: 11 people, 12.94%
  8. Sleep Disorder: 8 people, 9.41%
  9. High Blood Cholesterol: 8 people, 9.41%
  10. Hypersensitivity: 8 people, 9.41%

Other drugs people take *:

  1. Humira: 52 people, 61.18%
  2. Vitamin D: 22 people, 25.88%
  3. Vitamin C: 22 people, 25.88%
  4. Pantoprazole: 19 people, 22.35%
  5. Vitamin D3: 15 people, 17.65%
  6. Flovent: 14 people, 16.47%
  7. Vitamin B12: 13 people, 15.29%
  8. Zyrtec: 12 people, 14.12%
  9. Zeaxanthin: 12 people, 14.12%
  10. Nicoderm Cq: 12 people, 14.12%

Other side effects people have besides Procedural pain *:

  1. Pain: 33 people, 38.82%
  2. Weight Decreased: 26 people, 30.59%
  3. Nausea (feeling of having an urge to vomit): 23 people, 27.06%
  4. Fever: 17 people, 20.00%
  5. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 16 people, 18.82%
  6. Stress And Anxiety: 16 people, 18.82%
  7. Insomnia (sleeplessness): 16 people, 18.82%
  8. Malaise (a feeling of general discomfort or uneasiness): 16 people, 18.82%
  9. Arthritis (form of joint disorder that involves inflammation of one or more joints): 15 people, 17.65%
  10. Joint Pain: 15 people, 17.65%

* Approximation only. Some reports may have incomplete information.


How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Drugs with ingredients of tocopherols and tocotrienols, their effectiveness, alternatives and more:

How the study uses the data?

The study uses data from the FDA. It is based on tocopherols and tocotrienols. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

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DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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